Faculty of Biological Sciences

Prof Peter Stockley

BSc, London; PhD 1980, Cambridge.
Professor of Biological Chemistry
School of Molecular and Cellular Biology

Background: Studied Chemistry at Imperial College, London, before completing his PhD on Chromatin Structure in Prof. Jean Thomas' laboratory in Cambridge. Subsequently worked with Prof. Steve Harrison at Harvard on the mechanisms of virus assembly before joining the staff in Leeds in 1986.

Contact:  Miall 10.29 | +44(0) 113 34 33092 | email address for  

You can read more about Prof Stockley's interests here:
www.astbury.leeds.ac.uk/People/staffpage.php?StaffID=PGS

Research Interests

Protein-nucleic acid interactions, genetic regulatory mechanisms, virus assembly

The key feature of all living organisms that distinguishes them from simple chemical reactions is their ability to self-assemble complex macromolecular machines, from ribosomes to viruses, and the ability of those machines to participate in regulated functions. All these properties depend on the process of molecular recognition between gene products. We are studying a number of important model systems that allow us to dissect the molecular basis of such recognition events and hence the chemical underpinning of biological function. Our goals are to discover fundamental principles about the assembly and function of macromolecular machines, especially those involving protein-nucleic acid recognition, and to exploit this knowledge to create novel tools for research, diagnostics and/or therapy.

 

Faculty Research and Innovation



Studentship information

Undergraduate project topics:

  • Analysing transcription of chromatin templates
    Keywords: Transcription, recombinant protein purification, surface plasmon resonance
    (Laboratory)
  • Biochemical dissection of transcriptional initiation
    (Laboratory)
  • From RNA-protein interactions to virsu assembly
    (Laboratory)

Postgraduate studentship areas:

  • Protein-nucleic acid interactions, eukaryotic gene expression, Virus assembly, RNA aptamers as amyloid and virus inhibitors, bionanotechnology

See also:

Modules managed

BIOC1301 - Intro Inte Biochem Mol Process

Modules taught

BIOC1301 - Intro Inte Biochem Mol Process
BIOC1303 - Intro Biochem Problem Solving
BIOC2301 - Interm Integrated Biochemistry
BIOC2302 - Intermediate Biochem: Prac
BIOC2303 - Intermediate Biochem: Skills
BIOC3221/22/23/BIOL3210/MICR3211 b - ATU 30 - RNA therapy & diagnositcs
BIOL3306 - Biol Sciences Research Project
MICR3370 - Microbiology Research Programme

Centre membership:

Group Leader Prof Peter Stockley  (Professor of Biological Chemistry)

Protein-nucleic acid interactions, genetic regulatory mechanisms, virus assembly 


Dr Alexander  Borodavka  (Sir Henry Wellcome Post Doctoral Fellow)

Mr Christopher Kirkham  (Research Fellow)

Mrs Amy Barker  (Research Technician)

Dr Nikesh Patel  (Research Fellow)

Dr Amit Sharma  (Visiting Research Fellow)


Postgraduates

Amy Barker  
Christopher Kirkham  
Rachel Mahood  
Atul Mohan  
Christopher Rowley  
Emma Wroblewski  
Ruiyang Yan  

  • Analysing transcription of chromatin templates
    Keywords: Transcription, recombinant protein purification, surface plasmon resonance
    (Laboratory)
  • Biochemical dissection of transcriptional initiation
    (Laboratory)
  • From RNA-protein interactions to virsu assembly
    (Laboratory)
  • [chair] => [person_type] => Staff [has_publications] => [photo_exists] => 1 [publications] => [teaching] =>

    Modules managed

    BIOC1301 - Intro Inte Biochem Mol Process

    Modules taught

    BIOC1301 - Intro Inte Biochem Mol Process
    BIOC1303 - Intro Biochem Problem Solving
    BIOC2301 - Interm Integrated Biochemistry
    BIOC2302 - Intermediate Biochem: Prac
    BIOC2303 - Intermediate Biochem: Skills
    BIOC3221/22/23/BIOL3210/MICR3211 b - ATU 30 - RNA therapy & diagnositcs
    BIOL3306 - Biol Sciences Research Project
    MICR3370 - Microbiology Research Programme

    [group] =>

    Centre membership:

    Group Leader Prof Peter Stockley  (Professor of Biological Chemistry)

    Protein-nucleic acid interactions, genetic regulatory mechanisms, virus assembly 


    Dr Alexander  Borodavka  (Sir Henry Wellcome Post Doctoral Fellow)

    Mr Christopher Kirkham  (Research Fellow)

    Mrs Amy Barker  (Research Technician)

    Dr Nikesh Patel  (Research Fellow)

    Dr Amit Sharma  (Visiting Research Fellow)


    Postgraduates

    Amy Barker  
    Christopher Kirkham  
    Rachel Mahood  
    Atul Mohan  
    Christopher Rowley  
    Emma Wroblewski  
    Ruiyang Yan  

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