Leader of the David Rowlands group

Postgraduates

Kristopher Holmes  
James Kelly  

Davis MP; Bottley G; Beales LP; Killington RA; Rowlands DJ; Tuthill TJ Recombinant VP4 of human rhinovirus induces permeability in model membranes JOURNAL OF VIROLOGY 82 4169-4174, 2008
DOI:10.1128/JVI.01070-07

Bartlett NW; Walton RP; Edwards MR; Aniscenko J; Caramori G; Zhu J; Glanville N; Choy KJ; Jourdan P; Burnet J; Tuthill TJ; Pedrick MS; Hurle MJ; Plumpton C; Sharp NA; Bussell JN; Swallow DM; Schwarze J; Guy B; WAlmond J; Jeffery PK; Lloyd CM; Papi A; Killington RA; Rowlands DJ; Blair ED; Clarke NJ; Johnston SL Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation NATURE MEDICINE 14 199-204, 2008
DOI:10.1038/nm1713

Tuthill TJ; Rowlands DJ; Killington RA Picornavirus entry FUTURE VIROLOGY 2 343-351, 2007
DOI:10.2217/17460794.2.4.343

StGelais C; Tuthill TJ; Clarke DS; Rowlands DJ; Harris M; Griffin S Inhibition of hepatitis C virus p7 membrane channels in a liposome-based assay system ANTIVIRAL RESEARCH 76 48-58, 2007
DOI:10.1016/j.antiviral.2007.05.001

Rowlands DJ; Skehel JJ Fred Brown: 31 January 1925 - 20 February 2004. Biogr Mem Fellows R Soc 53 93-108, 2007

Tuthill TJ; Bubeck D; Rowlands DJ; Hogle JM Characterization of early steps in the poliovirus infection process: Receptor-decorated liposomes induce conversion of the virus to membrane-anchored entry-intermediate particles JOURNAL OF VIROLOGY 80 172-180, 2006
DOI:10.1128/JVI.80.1.172-180.2006

Ellingham M; Bunka DHJ; Rowlands DJ; Stonehouse NJ Selection and characterization of RNA aptamers to the RNA-dependent RNA polymerase from foot-and-mouth disease virus RNA-A PUBLICATION OF THE RNA SOCIETY 12 1970-1979, 2006
DOI:10.1261/rna.161006

McCormick CJ; Brown D; Griffin S; Challinor L; Rowlands DJ; Harris M A link between translation of the hepatitis C virus polyprotein and polymerase function; possible consequences for hyperphosphorylation of NS5A JOURNAL OF GENERAL VIROLOGY 87 93-102, 2006
DOI:10.1099/vir.0.81180.0

Clarke D; Griffin S; Beales L; Gelais CS; Burgess S; Harris M; Rowlands D Evidence for the formation of a heptameric ion channel complex by the hepatitis C virus p7 protein in vitro JOURNAL OF BIOLOGICAL CHEMISTRY 281 37057-37068, 2006
DOI:10.1074/jbc.M602434200

McCormick CJ; Maucourant S; Griffin S; Rowlands DJ; Harris M Tagging of NS5A expressed from a functional hepatitis C virus replicon JOURNAL OF GENERAL VIROLOGY 87 635-640, 2006
DOI:10.1099/vir.0.81553-0

Fry EE; Stuart DI; Rowlands DJ The structure of foot-and-mouth disease virus FOOT AND MOUTH DISEASE VIRUS 288 71-101, 2005

Fry EE; Stuart DI; Rowlands DJ The structure of foot-and-mouth disease virus Current Topics in Microbiology and Immunology 288 71-101, 2005

Griffin S; Clarke D; McCormick C; Rowlands D; Harris M Signal peptide cleavage and internal targeting signals direct the hepatitis C virus p7 protein to distinct intracellular membranes JOURNAL OF VIROLOGY 79 15525-15536, 2005
DOI:10.1128/JVI.79.24.15525-15536.2005

Mahy BW; Rowlands DJ In memoriam Fred Brown (1925-2004) - Obituary ARCHIVES OF VIROLOGY 150 199-200, 2005
DOI:10.1007/s00705-004-0442-4

Gilbert RJC; Beales L; Blond D; Simon MN; Lin BY; Chisari FV; Stuart DI; Rowlands DJ Hepatitis B small surface antigen particles are octahedral PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102 14783-14788, 2005
DOI:10.1073/pnas.0505062102

McCormick CJ; Challinor L; Macdonald A; Rowlands DJ; Harris M Introduction of replication-competent hepatitis C virus transcripts using a tetracycline-regulable baculovirus delivery system JOURNAL OF GENERAL VIROLOGY 85 429-439, 2004
DOI:10.1099/vir.0.19676-0

Rowlands DJ Foot-and-Mouth Disease peptide vaccines In Current Perspectives - Foot-and-Mouth Disease Virus , 2004

Xiao C; Tuthill TJ; Kelly CMB; Challinor LJ; Chipman PR; Killington RA; Rowlands DJ; Craig A; Rossmann MG Discrimination among rhinovirus serotypes for a variant ICAM-1 receptor molecule JOURNAL OF VIROLOGY 78 10034-10044, 2004
DOI:10.1128/JVI.78.18.10034-10044.2004

Griffin SDC; Harvey R; Clarke DS; Barclay WS; Harris M; Rowlands DJ A conserved basic loop in hepatitis C virus p7 protein is required for amantadine-sensitive ion channel activity in mammalian cells but is dispensable for localization to mitochondria JOURNAL OF GENERAL VIROLOGY 85 451-461, 2004
DOI:10.1099/vir.0.19634-0

Tuthill TJ; Papadopoulos NG; Jourdan P; Challinor LJ; Sharp NA; Plumpton C; Shah K; Barnard S; Dash L; Burnet J; Killington RA; Rowlands DJ; Clarke NJ; Blair ED; Johnston SL Mouse respiratory epithelial cells support efficient replication of human rhinovirus JOURNAL OF GENERAL VIROLOGY 84 2829-2836, 2003
DOI:10.1099/vir.0.19109-0

O'Farrell D; Trowbridge R; Rowlands DJ; Jaeger J Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): Structural evidence for nucleotide import and De-novo initiation Journal of Molecular Biology 326 1025-1035, 2003
DOI:10.1016/S0022-2836(02)01439-0

Griffin SDC; Beales LP; Clarke DS; Worsfold O; Evans SD; Jaeger J; Harris MPG; Rowlands DJ The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, Amantadine FEBS LETTERS 535 34-38, 2003
DOI:10.1016/S0014-5793(02)03851-6

Beales LP; Holzenburg A; Rowlands DJ Viral internal ribosome entry site structures segregate into two distinct morphologies JOURNAL OF VIROLOGY 77 6574-6579, 2003
DOI:10.1128/JVI.77.11.6574-6579.2003

Rowlands DJ Special issue - Foot-and-mouth disease - Preface VIRUS RESEARCH 91 1-1, 2003
DOI:10.1016/S0168-1702(02)00264-2

McCormick CJ; Rowlands DJ; Harris M Efficient delivery and regulable expression of hepatitis C virus full-length and minigenome constructs in hepatocyte-derived cell lines using baculovirus vectors JOURNAL OF GENERAL VIROLOGY 83 383-394, 2002

Beales LP; Rowlands DJ; Holzenburg A The internal ribosome entry site (IRES) of hepatitis C virus visualized by electron microscopy RNA-A PUBLICATION OF THE RNA SOCIETY 7 661-670, 2001
DOI:10.1017/S1355838201001406

Aoubala M; Holt J; Clegg RA; Rowlands DJ; Harris M The inhibition of cAMP-dependent protein kinase by full-length hepatitis C virus NS3/4A complex is due to ATP hydrolysis JOURNAL OF GENERAL VIROLOGY 82 1637-1646, 2001

Sharma A; Rao Z; Fry E; Booth T; Jones EY; Rowlands DJ; Simmons DL; Stuart DI Specific interactions between human integrinα(v)β3 and chimeric hepatitis B virus core particles bearing the receptor-binding epitope of foot-and-mouth disease virus Virology 239 150-157, 1997

Reynolds JE; Kaminski A; Carroll AR; Clarke BE; Rowlands DJ; Jackson RJ Internal initiation of translation of hepatitis C virus RNA: The ribosome entry site is at the authentic initiation codon. RNA 2 867-878, 1996

Honda M; Ping LH; Rijnbrand RCA; Amphlet A; Clarke B; Rowlands DJ; Lemon SM Structural requirements for initiation of translation by internal ribosome entry within genome-length hepatitis C virus RNA. Virology 222 31-42, 1996

Curry S; Fry E; Blakemore W; AbuGhaazaleh R; Jackson T; King A; Lea S; Newman J; Rowlands DJ; Stuart D Perturbations in the surface structure of A22 Iraq foot-and-mouth disease virus accompanying coupled changes in host cell specificity and antigenicity Structure 4 135-145, 1996

Chambers M; Dougan G; Newman J; Brown F; Crowther J; Paul Mould A; Humphries MJ; Francis MJ; Clarke B; Brown AL; Rowlands D Chimeric hepatitis B virus core particles as probes for studying peptide-integrin interactions Journal of Virology 70 4045-4052, 1996

Pegna M; Molinari H; Zetta L; Melacini G; Gibbons WA; Brown F; Rowlands DJ; Chan E; Mascagni P The solution conformational features of two highly homologous antigenic peptides of Foot and Mouth Disease Virus serotype A, variants A and USA, correlate with their serological properties. Journal of Peptide Science 2 91-105, 1996

Rowlands DJ Editorship: Virus Research Virus Research 91 -,