Faculty of Biological Sciences

Dr Sergei Krivov

MS, Novosibirsk, Russia PhD 1999, Novosibirsk, Russia
RCUK Academic Research Fellow
School of Molecular and Cellular Biology

Background: Life manifests itself through complex dynamics across many scales, from “wiggling and jiggling of atoms” (protein folding) to transcription dynamics in gene regulatory networks, disease dynamics and population dynamics. Advances in experimental techniques resulted in availability of multidimensional, time-resolved data about dynamical processes. On the other hand, advances in computer hardware and simulation algorithms made it possible to obtain detailed dynamical picture of real-life biological processes on a computer. Computational experiments became a vital component of researches arsenal, as was highlighted by the recent Nobel prize awarded to three computational chemists. The large size of datasets generated by computer simulations or experiments makes the development of automated analysis tools very important, practically and conceptually. In our lab we focus on the development of an original state of the art approach which focuses specifically on accurate description of the dynamics and its application to the analysis of in-silico and in-vitro data.

Contact:  Garstang 10.132, +44(0) 113 34 33141, email address for  

You can read more about Dr Krivov's interests here:
http://www.astbury.leeds.ac.uk/people/staff/staffpage.php?StaffID=SK

Research Interests

Quantitative analysis of complex biological dynamics.

Faculty Research and Innovation



Studentship information

Undergraduate project topics:

  • Free energy landscape analysis of realistic protein folding simulations.

See also:

Modules managed

BIOL5172M - Practical Bioinformatics

Modules taught

BIOC1303 - Introductory Biochemistry: Problem Solving and Data Handling
BIOC2303 - Intermediate Biochemistry: Skills
BIOL2301 - Intermediate Skills for Biological Sciences
BIOL2301/03/05/MICR2320/BIOL3400 - BIOL/BIOC/MICR advanced skills/Skills in the Cell Biology of Human Disease
BIOL5172M - Practical Bioinformatics
MICR3370 - Microbiology with Virology Research Project

Committees

Member of Masters Taught Student Education Committee

Group Leader Dr Sergei Krivov  (RCUK Academic Research Fellow)

Quantitative analysis of complex biological dynamics.