Miss Ruth Hughes

Research Felow
School of Molecular and Cellular Biology

Contact: Astbury 8.104, +44(0) 113 34 Ext. 31623, email address for  

Lopata A, Hughes R, Tiede C, Heissler SM, Sellers JR, Knight PJ, Tomlinson D, Peckham M Affimer proteins for F-actin: Novel affinity reagents that label F-actin in live and fixed cells Scientific Reports 8, 2018
DOI:10.1038/s41598-018-24953-4
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Parker F, Batchelor M, Wolny M, Hughes R, Knight PJ, Peckham M A1603P and K1617del, Mutations inβ-Cardiac Myosin Heavy Chain that Cause Laing Early-Onset Distal Myopathy, Affect Secondary Structure and Filament Formation In Vitro and In Vivo Journal of Molecular Biology 430 1459-1478, 2018
DOI:10.1016/j.jmb.2018.04.006
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Bedford R, Tiede C, Hughes R, Curd A, McPherson MJ, Peckham M, Tomlinson DC Alternative reagents to antibodies in imaging applications, 2017
DOI:10.1007/s12551-017-0278-2
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Tiede C, Bedford R, Heseltine SJ, Smith G, Wijetunga I, Ross R, Alqallaf D, Roberts APE, Balls A, Curd A, Hughes RE, Martin H, Needham SR, Zanetti-Domingues LC, Sadigh Y, Peacock TP, Tang AA, Gibson N, Kyle H, Platt GW, Ingram N, Taylor T, Coletta LP, Manfield I, Knowles M, Bell S, Esteves F, Maqbool A, Prasad RK, Drinkhill M, Bon RS, Patel V, Goodchild SA, Martin-Fernandez M, Owens RJ, Nettleship JE, Webb ME, Harrison M, Lippiat JD, Ponnambalam S, Peckham M, Smith A, Ferrigno PK, Johnson M, McPherson MJ, Tomlinson DC Affimer proteins are versatile and renewable affinity reagents eLife 6, 2017
DOI:10.7554/eLife.24903
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Diggle CP, Martinez-Garay I, Molnar Z, Brinkworth MH, White E, Fowler E, Hughes R, Hayward BE, Carr IM, Watson CM, Crinnion L, Asipu A, Woodman B, Coletta PL, Markham AF, Dear TN, Bonthron DT, Peckham M, Morrison EE, Sheridan E Atubulin alpha 8 mouse knockout model indicates a likely role in spermatogenesis but not in brain development PLoS ONE 12, 2017
DOI:10.1371/journal.pone.0174264
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Bacon T, Seiler C, Wolny M, Hughes R, Watson P, Schwabe J, Grigg R, Peckham M Histone deacetylase 3 indirectly modulates tubulin acetylation Biochemical Journal 472 367-377, 2015
DOI:10.1042/BJ20150660
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Makowska KA, Hughes RE, White KJ, Wells CM, Peckham M Specific Myosins Control Actin Organization, Cell Morphology, and Migration in Prostate Cancer Cells Cell Reports 13 2118-2125, 2015
DOI:10.1016/j.celrep.2015.11.012
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Burnham MP, Sharpe PM, Garner C, Hughes R, Pollard CE, Bowes J Investigation of connexin 43 uncoupling and prolongation of the cardiac QRS complex in preclinical and marketed drugs British Journal of Pharmacology 171 4808-4819, 2014
DOI:10.1111/bph.12554
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