Dr Emma Hesketh

Cryo-Electron Microscopy Support Scientist and Research Fellow
School of Molecular and Cellular Biology

Contact: Other/Unknown Roger Stevens 5.40, +44(0) 113 34 38957, email address for  

Hesketh EL, Saunders K, Fisher C, Potze J, Stanley J, Lomonossoff GP, Ranson NA The 3.3Å structure of a plant geminivirus using cryo-EM Nature Communications 9, 2018
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Drulyte I, Johnson RM, Hesketh EL, Hurdiss DL, Scarff CA, Porav SA, Ranson NA, Muench SP, Thompson RF Approaches to altering particle distributions in cryo-electron microscopy sample preparation Acta Crystallographica Section D: Structural Biology 74 560-571, 2018
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Meshcheriakova Y, Durrant A, Hesketh EL, Ranson NA, Lomonossoff GP Combining high-resolution cryo-electron microscopy and mutagenesis to develop cowpea mosaic virus for bionanotechnology Biochemical Society Transactions 45 1263-1269, 2017
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Hesketh EL, Meshcheriakova Y, Thompson RF, Lomonossoff GP, Ranson NA The structures of a naturally empty cowpea mosaic virus particle and its genome-containing counterpart by cryo-electron microscopy Scientific Reports 7, 2017
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Huynh NAT, Hesketh EAL, Saxena P, Meshcheriakova Y, Ku YC, Hoang LAT, Johnson JAE, Ranson NAA, Lomonossoff GAP, Reddy VAS Crystal Structure and Proteomics Analysis of Empty Virus-like Particles of Cowpea Mosaic Virus Structure 24 567-575, 2016
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Wilson RHC, Hesketh EL, Coverley D The nuclear matrix: Fractionation techniques and analysis Cold Spring Harbor Protocols 2016 5-10, 2016
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Wilson RHC, Hesketh EL, Coverley D Preparation of the nuclear matrix for parallel microscopy and biochemical analyses Cold Spring Harbor Protocols 2016 50-56, 2016
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Hesketh EL, Meshcheriakova Y, Dent KC, Saxena P, Thompson RF, Cockburn JJ, Lomonossoff GP, Ranson NA Mechanisms of assembly and genome packaging in an RNA virus revealed by high-resolution cryo-EM Nature Communications 6, 2015
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Hesketh EL, Parker-Manuel RP, Chaban Y, Satti R, Coverley D, Orlova EV, Chong JPJ DNA induces conformational changes in a recombinant human minichromosome maintenance complex Journal of Biological Chemistry 290 7973-7979, 2015
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Hesketh EL, Knight JRP, Wilson RHC, Chong JPJ, Coverley D Transient association of MCM complex proteins with the nuclear matrix during initiation of mammalian DNA replication Cell Cycle 14 333-341, 2015
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