Faculty of Biological Sciences

Dr Emma Hesketh

Cryo-Electron Microscopy Support Scientist and Research Fellow
School of Molecular and Cellular Biology

Contact:  Other/Unknown Roger Stevens 5.40, +44(0) 113 34 38957, email address for  

Hesketh EL, Meshcheriakova Y, Thompson RF, Lomonossoff GP, Ranson NA The structures of a naturally empty cowpea mosaic virus particle and its genome-containing counterpart by cryo-electron microscopy Scientific Reports 7 -, 2017
DOI:10.1038/s41598-017-00533-w
View abstract

Meshcheriakova Y, Durrant A, Hesketh EL, Ranson NA, Lomonossoff GP Combining high-resolution cryo-electron microscopy and mutagenesis to develop cowpea mosaic virus for bionanotechnology. Biochemical Society transactions -, 2017
DOI:10.1042/bst20160312
View abstract

Huynh NAT, Hesketh EAL, Saxena P, Meshcheriakova Y, Ku YC, Hoang LAT, Johnson JAE, Ranson NAA, Lomonossoff GAP, Reddy VAS Crystal Structure and Proteomics Analysis of Empty Virus-like Particles of Cowpea Mosaic Virus Structure 24 567-575, 2016
DOI:10.1016/j.str.2016.02.011
View abstract

Wilson RHC, Hesketh EL, Coverley D Preparation of the nuclear matrix for parallel microscopy and biochemical analyses Cold Spring Harbor Protocols 2016 50-56, 2016
DOI:10.1101/pdb.prot083758
View abstract

Wilson RHC, Hesketh EL, Coverley D The nuclear matrix: Fractionation techniques and analysis Cold Spring Harbor Protocols 2016 5-10, 2016
DOI:10.1101/pdb.top074518
View abstract

Hesketh EL, Meshcheriakova Y, Dent KC, Saxena P, Thompson RF, Cockburn JJ, Lomonossoff GP, Ranson NA Mechanisms of assembly and genome packaging in an RNA virus revealed by high-resolution cryo-EM Nature Communications 6 -, 2015
DOI:10.1038/ncomms10113
View abstract

Hesketh EL, Parker-Manuel RP, Chaban Y, Satti R, Coverley D, Orlova EV, Chong JPJ DNA induces conformational changes in a recombinant human minichromosome maintenance complex Journal of Biological Chemistry 290 7973-7979, 2015
DOI:10.1074/jbc.M114.622738
View abstract

Hesketh EL, Knight JRP, Wilson RHC, Chong JPJ, Coverley D Transient association of MCM complex proteins with the nuclear matrix during initiation of mammalian DNA replication Cell Cycle 14 333-341, 2015
DOI:10.4161/15384101.2014.980647
View abstract