Faculty of Biological Sciences

Dr Henry Greathead

BSc, PhD May 1997, Nottingham
Lecturer
School of Biology

Contact:  Manton 8.21b | +44(0) 113 34 33063 | email address for  

You can read more about Dr Greathead's interests here:
www.biology.leeds.ac.uk/Centres/cas/great.htm

Research Interests

Ruminants: nutrition; growth; metabolism; Plant extracts/secondary metabolites

Animals are what they eat!

How does what an animal eats effect its performance? This is of both fundamental and applied interest. Plants produce an immense diversity of plant secondary metabolites, the non-ubiquitous products of plant secondary metabolism. Many of these compounds are bioactive. It is of fundamental interest to understand how these compounds interact with living organisms, from a molecular level (nutrigenomics) right through to the whole organism itself. Why? - because it will improve our understanding of how common chemicals in the diets of animals affect their performance. The applied interest is being driven by the growing legislation against the prophylactic use of performance enhancing medicinal feed-additives for which bioactive plant secondary metabolites are a potential and sustainable alternative.

Research over the last six years, aimed at identifying novel strategies to enhance dairy cow performance by modifying the rumen microflora, has identified individual plant extracts, namely eugenol and cinnamaldehyde, that have potential to enhance the efficiency of protein and energy metabolism in the rumen. The rumen bacteria and Archaea involved in these effects are under investigation.

A project investigating the use of plant secondary metabolites as anticoccidial feed additives in broiler chickens has shown that while thymol and carvacrol appear to have no negative impact on the E. acurvulina parasite itself, thymol may have a role to play in controlling coccidiosis through its ability to limit the pathological impact of the disease.

Future work will strive to understand how plant secondary metabolites elicit their effects. In particular how they might interact with genes expressed in enterocytes. Sources of funding include the EU, BBSRC and industry.

 

Current Projects

  • The use of plant extracts to control coccidiosis in broiler chickens
  • Plant extracts as a strategy to improve sow and litter performance
 

Faculty Research and Innovation


Studentship information

Postgraduate studentship areas:

  • Bioactive phytocompounds, animal growth and metabolism

See also:

Admin roles

External Examiner (taught course): Harper Adams University
FBS UGTSEC
UG Admissions Tutor

Modules managed

BLGY1211 - Applied Biology and Agriculture
BLGY1236 - Practical Applied Biology
BLGY2142 - Animal Nutrition and Metabolism
BLGY3271 - Animal Metabolism and Nutrition

Modules taught

BLGY1115 - Introduction to Cell Biology
BLGY1211 - Applied Biology and Agriculture
BLGY1236 - Practical Applied Biology
BLGY1300 - Coastal and Upland Habitats Field Course
BLGY1304 - Research Exp. Skills Level 1
BLGY2100 - Enhanced Study Skills for Biologists
BLGY2142 - Animal Nutrition and Metabolism
BLGY2225 - Sustainable Food Production
BLGY3021 - Research Project
BLGY3105 - Applied Animal Science
BLGY3271 - Animal Metabolism and Nutrition
BLGY3340 - Biology Research Projects
BLGY5380M - Extended Research Project

Committees

Member of Undergraduate School Taught Student Education Committee

Group Leader Dr Henry Greathead  (Lecturer)

Ruminants: nutrition; growth; metabolism; Plant extracts/secondary metabolites 


Postgraduates

Katie McDermott  

Benchaar C; Greathead H Essential oils and opportunities to mitigate enteric methane emissions from ruminants Animal Feed Science and Technology 166-167 338-355, 2011
DOI:10.1016/j.anifeedsci.2011.04.024
View abstract

Benchaar C; Hristov AN; Greathead H Essential oils as feed additives in ruminant nutrition In in Animal Nutrition , 2009
View abstract

Kamel C; Greathead HMR; Tejido ML; Ranilla MJ; Carro MD Effects of allicin and diallyl disulfide on in vitro rumen fermentation of a mixed diet ANIM FEED SCI TECH 145 351-363, 2008
DOI:10.1016/j.anifeedsci.2007.05.050

Greathead HMR; Dawson JM; Craigon J; Sessions VA; Scollan ND; Buttery PJ Fat and protein metabolism in growing steers fed either grass silage or dried grass BRIT J NUTR 95 27-39, 2006
DOI:10.1079/BJN20051568

Ilsley SE; Miller HM; Greathead HMR; Kamel C Plant extracts as supplements for lactating sows: effects on piglet performance, sow food intake and diet digestibility ANIM SCI 77 247-254, 2003

Greathead HMR Plants and plant extracts for improving animal productivity Proceedings of the Nutrition Society 62 279-290, 2003

Ilsley SE; Miller HM; Greathead HMR; Kamel C Supplementation of sow diets with plant extracts enhances piglet growth prior to weaning, 2002

Ibrir F; Greathead HMR; Forbes JM Effect of thymol and carvacrol on coccidia infected chickens, 2002

Greathead HMR Plant extracts enhance sow lactation performance, 2002

Greathead HMR; Dawson JM; Scollan ND; Buttery PJ In vivo measurement of lipogenesis in ruminants using [1-C-14]acetate BRIT J NUTR 86 37-44, 2001

Ibrir F; Greathead HMR; Forbes JM The effect of thymol/carvacol treatments on the performance of broiler chickens infected with Elimeria acervulina, 2001

Greathead HMR; Dawson JM; Scollan ND; Buttery PJ In vivo measurement of lipogenesis in ruminants using [1-14C]acetate British Journal of Nutrition 86 37-44, 2001

Greathead HMR; Forbes JM; Beaumont D; Kamel C The effect of a formulation of natural essential oils used as an additive with milk replacer and a compound feed on the feed efficiency of calves., 2000

Dawson JM; Greathead HMR; Sessions VA; Tye FM; Buttery PJ Effect of gastric inhibitory polypeptide on bovine fat metabolism Comparative Biochemistry and Physiology. Part B: Comparative Biochemistry 123 79-88, 1999

Greathead HMR The interaction between nutritional status and growth hormone in young cattle: differential responsiveness of fat and protein metabolism Unknown Journal - Requested journal to be added to ULPD 79 275-286, 1998

Greathead HMR Whole-body protein metabolism in cattle fed on grass silage and dried grass at different intakes, 1997

Greathead HMR Fat synthesis in different depots of cattle given grass silage and dried grass at different intakes, 1996

Webber J; Taylor J; Greathead HMR; Dawson JM; Buttery PJ; MacDonald IA The effects of fasting on the thermogenic, metabolic and cardiovascular responses to infused adrenaline British Journal of Nutrition 74 477-490, 1995

Webber J; Taylor J; Greathead HMR; Dawson JM; Buttery PJ; MacDonald IA A comparison of the thermogenic, metabolic and haemodynamic responses to infused adrenaline in lean and obese subjects International Journal of Obesity 18 717-724, 1994

Greathead HMR; Dawson JM; McAllan AB; Buttery PJ Whole-body fat metabolism in cattle fed forage-based diets, 1994

Webber J; Taylor J; Greathead HMR; Dawson JM; Buttery PJ; MacDonald IA The effects of adrenaline on fatty acid turnover and oxidation in lean and obese subjects, 1994

Dawson JM; Greathead HMR; Hachey DL; Reeds PJ; Buttery PJ; Pell JM; Beever DE The interaction between plane of nutrition and response to growth hormone on fat and protein metabolism in cattle, 1993