Faculty of Biological Sciences

Prof Stuart Egginton

BSc (Bangor), PhD (St Andrews), DSc (Birmingham)
Leadership Chair in Exercise Science
School of Biomedical Sciences

Background: BSc(Hons) Zoology, University of Wales, Bangor; PhD Physiology, University of St. Andrews, Fife; Postdoctoral Fellow at University of Maine, Orono (USA) and University of Birmingham; Lecturer, Senior Lecturer and Reader in Cardiovascular Physiology at University of Birmingham

Contact:  Worsley 10.100 | +44(0) 113 34 32264 | email address for Prof Stuart Egginton 

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Modules taught

BMSC1215 - Life in the Extreme: Ultra Human Physiology
BMSC3233/34/35/36/37 - ATUs - BMS specific
SPSC1211 - Tutorial and Practical Skills in Sport and Exercise Science
SPSC2218 - Professional and Res Skills
SPSC3061 - Research Project in Sport and Exercise Science II
SPSC3301 - Inter-disciplinary Issues in Sport and Exercise Science
SPSC3321 - Advanced Exercise Physiology

Wragg JW; Durant S; McGettrick HM; Sample KM; Egginton S; Bicknell R Shear stress regulated gene expression and angiogenesis in vascular endothelium. Microcirculation -, 2014
DOI:10.1111/micc.12119
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Vornanen M; Haverinen J; Egginton S Acute heat tolerance of cardiac excitation in the brown trout (Salmo trutta fario) JOURNAL OF EXPERIMENTAL BIOLOGY 217 299-309, 2014
DOI:10.1242/jeb.091272

Egginton S; Birot O Angiogenesis: growth points. Microcirculation -, 2014
DOI:10.1111/micc.12131
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Egginton S; May S; Deveci D; Hauton D Is cold acclimation of benefit to hibernating rodents? J Exp Biol 216 2140-2149, 2013
DOI:10.1242/jeb.079160
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Luu NT; Glen KE; Egginton S; Rainger GE; Nash GB Integrin-substrate interactions underlying shear-induced inhibition of the inflammatory response of endothelial cells. Thromb Haemost 109 298-308, 2013
DOI:10.1160/TH12-06-0400
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Lotfi S; Patel AS; Mattock K; Egginton S; Smith A; Modarai B Towards a more relevant hind limb model of muscle ischaemia. Atherosclerosis 227 1-8, 2013
DOI:10.1016/j.atherosclerosis.2012.10.060
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Patel AS; Smith A; Nucera S; Biziato D; Saha P; Attia RQ; Humphries J; Mattock K; Grover SP; Lyons OT; Guidotti LG; Siow R; Ivetic A; Egginton S; Waltham M; Naldini L; De Palma M; Modarai B TIE2-expressing monocytes/macrophages regulate revascularization of the ischemic limb EMBO MOLECULAR MEDICINE 5 858-869, 2013
DOI:10.1002/emmm.201302752

Syeda F; Hauton D; Young S; Egginton S How ubiquitous is endothelial NOS? COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR&INTEGRATIVE PHYSIOLOGY 166 207-214, 2013
DOI:10.1016/j.cbpa.2013.05.027

Dhillon SS; Dóró E; Magyary I; Egginton S; Sík A; Müller F Optimisation of embryonic and larval ECG measurement in zebrafish for quantifying the effect of QT prolonging drugs. PLoS One 8 e60552-, 2013
DOI:10.1371/journal.pone.0060552
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Patel AS; Smith A; Nucera S; Biziato D; Saha P; Attia RQ; Humphries J; Grover SP; Mattock K; Lyons OT; Guidotti LG; Siow R; Ivetic A; Egginton S; Waltham M; Naldini L; De Palma M; Modarai B TIE2-expressing monocytes regulate revascularisation of the ischaemic limb, 2013

Hughes CE; Radhakrishnan UP; Lordkipanidzé M; Egginton S; Dijkstra JM; Jagadeeswaran P; Watson SP G6f-like is an ITAM-containing collagen receptor in thrombocytes. PLoS One 7 e52622-, 2012
DOI:10.1371/journal.pone.0052622
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Glen K; Luu NT; Ross E; Buckley CD; Rainger GE; Egginton S; Nash GB Modulation of functional responses of endothelial cells linked to angiogenesis and inflammation by shear stress: differential effects of the mechanotransducer CD31. J Cell Physiol 227 2710-2721, 2012
DOI:10.1002/jcp.23015
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Hussain A; Steimle M; Hoppeler H; Baum O; Egginton S The vascular-disrupting agent combretastatin impairs splitting and sprouting forms of physiological angiogenesis. Microcirculation 19 296-305, 2012
DOI:10.1111/j.1549-8719.2012.00160.x
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Al-Shammari AA; Gaffney EA; Egginton S Re-evaluating the Use of Voronoi Tessellations in the Assessment of Oxygen Supply from Capillaries in Muscle Bulletin of Mathematical Biology 74 2204-2231, 2012
DOI:10.1007/s11538-012-9753-x
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Cudmore MJ; Ahmad S; Sissaoui S; Ramma W; Ma B; Fujisawa T; Al-Ani B; Wang K; Cai M; Crispi F; Hewett PW; Gratacos E; Egginton S; Ahmed A Loss of Akt activity increases circulating soluble endoglin release in preeclampsia: identification of inter-dependency between Akt-1 and heme oxygenase-1 EUROPEAN HEART JOURNAL 33 1150-1158, 2012
DOI:10.1093/eurheartj/ehr065

Egginton S In vivo shear stress response. Biochem Soc Trans 39 1633-1638, 2011
DOI:10.1042/BST20110715
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Egginton S; Bicknell R Advances in the cellular and molecular biology of angiogenesis. Biochem Soc Trans 39 1551-1555, 2011
DOI:10.1042/BST20110749
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Turan N; Kalko S; Stincone A; Clarke K; Sabah A; Howlett K; Curnow SJ; Rodriguez DA; Cascante M; O'Neill L; Egginton S; Roca J; Falciani F A systems biology approach identifies molecular networks defining skeletal muscle abnormalities in chronic obstructive pulmonary disease. PLoS Comput Biol 7 e1002129-, 2011
DOI:10.1371/journal.pcbi.1002129
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Egginton S; Badr I; Williams J; Hauton D; Baan GC; Jaspers RT Physiological angiogenesis is a graded, not threshold, response. J Physiol 589 195-206, 2011
DOI:10.1113/jphysiol.2010.194951
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Egginton S Physiological factors influencing capillary growth. Acta Physiol (Oxf) 202 225-239, 2011
DOI:10.1111/j.1748-1716.2010.02194.x
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Egginton S; Kumar P HIGH ALTITUDE TOLERANCE IS NOT DETERMINED BY CLASS JOURNAL OF APPLIED PHYSIOLOGY 111 1524-1524, 2011

Young S; Egginton S Temperature acclimation of gross cardiovascular morphology in common carp (Cyprinus carpio) JOURNAL OF THERMAL BIOLOGY 36 475-477, 2011
DOI:10.1016/j.jtherbio.2011.06.013

Scott GR; Schulte PM; Egginton S; Scott ALM; Richards JG; Milsom WK Molecular Evolution of Cytochrome c Oxidase Underlies High-Altitude Adaptation in the Bar-Headed Goose MOLECULAR BIOLOGY AND EVOLUTION 28 351-363, 2011
DOI:10.1093/molbev/msq205

Robinson E; Egginton S; Davison W Warm-induced bradycardia and cold-induced tachycardia: mechanisms of cardiac and ventilatory control in a warm-acclimated Antarctic fish POLAR BIOLOGY 34 371-379, 2011
DOI:10.1007/s00300-010-0891-z

Rae PC; Kelly RD; Egginton S; St John JC Angiogenic potential of endothelial progenitor cells and embryonic stem cells Vascular Cell 3 -, 2011
DOI:10.1186/2045-824X-3-11
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Egginton S; Kumar P Comments on point:counterpoint: High altitude is/is not for the birds! Journal of Applied Physiology 111 1524-1524, 2011
DOI:10.1152/japplphysiol.01117.2011

Egginton S; Kumar P Comments on point:counterpoint: High altitude is/is not for the birds! Journal of Applied Physiology 111 1524-1524, 2011

Hauton D; May S; Sabharwal R; Deveci D; Egginton S Cold-impaired cardiac performance in rats is only partially overcome by cold acclimation. J Exp Biol 214 3021-3031, 2011
DOI:10.1242/jeb.053587
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Ormerod JO; Ashrafian H; Maher AR; Arif S; Steeples V; Born GV; Egginton S; Feelisch M; Watkins H; Frenneaux MP The role of vascular myoglobin in nitrite-mediated blood vessel relaxation. Cardiovasc Res 89 560-565, 2011
DOI:10.1093/cvr/cvq299
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Egginton S; Syeda F Design and physiology of capillaries and secondary circulation | Capillaries, Capillarity, and Angiogenesis In Encyclopedia of Fish Physiology: From Genome to Environment , 2011
DOI:10.1016/B978-0-12-374553-8.00049-6
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Egginton S Angiogenesis - may the force be with you! J Physiol 588 4615-4616, 2010
DOI:10.1113/jphysiol.2010.201012

Egginton S Muscle capillary supply takes the load. J Physiol 588 4607-4608, 2010
DOI:10.1113/jphysiol.2010.200378

Egginton S; Gaffney E Tissue capillary supply--it's quality not quantity that counts! Exp Physiol 95 971-979, 2010
DOI:10.1113/expphysiol.2010.053421
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Hill JV; Egginton S Control of Branchial Artery Tone in Fish: Effects of Environmental Temperature and Phylogeny PHYSIOLOGICAL AND BIOCHEMICAL ZOOLOGY 83 33-42, 2010
DOI:10.1086/648469

Egginton S; Gaffney E Tissue capillary supply - It's quality not quantity that counts! Experimental Physiology 95 971-979, 2010
DOI:10.1002/(SICI)1097-0185(199809)252:1
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Egginton S; White MJ 2010 winter games themed issue Experimental Physiology 95 402-403, 2010

Herbert JMJ; Buffa FM; Vorschmitt H; Egginton S; Bicknell R A new procedure for determining the genetic basis of a physiological process in a non-model species, illustrated by cold induced angiogenesis in the carp BMC GENOMICS 10 -, 2009
DOI:10.1186/1471-2164-10-490

Young S; Egginton S Allometry of skeletal muscle fine structure allows maintenance of aerobic capacity during ontogenetic growth. J Exp Biol 212 3564-3575, 2009
DOI:10.1242/jeb.029512
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Hauton D; Coney AM; Egginton S Both substrate availability and utilisation contribute to the defence of core temperature in response to acute cold. Comp Biochem Physiol A Mol Integr Physiol 154 514-522, 2009
DOI:10.1016/j.cbpa.2009.08.008
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Campbell H; Davison W; Fraser KP; Peck LS; Egginton S Heart rate and ventilation in Antarctic fishes are largely determined by ecotype. J Fish Biol 74 535-552, 2009
DOI:10.1111/j.1095-8649.2008.02141.x
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Ahmed SK; Williams JL; Drake-Lee A; Egginton S Staining of nasal mucosa to examine remodelling. J Laryngol Otol 123 234-237, 2009
DOI:10.1017/S0022215108003381
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Egginton S Invited review: activity-induced angiogenesis. Pflugers Arch 457 963-977, 2009
DOI:10.1007/s00424-008-0563-9
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Clough GF; Egginton S Vasomotion and insulin-mediated capillary recruitment - Part of the explanation? Journal of Physiology 587 3407-3408, 2009
DOI:10.1113/jphysiol.2009.174557

Young S; Egginton S Allometry of skeletal muscle fine structure allows maintenance of aerobic capacity during ontogenetic growth Journal of Experimental Biology 212 3564-3575, 2009
DOI:10.1046/j.1365-2656.1999.00337.x
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Scott GR; Egginton S; Richards JG; Milsom WK Evolution of muscle phenotype for extreme high altitude flight in the bar-headed goose PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES 276 3645-3653, 2009
DOI:10.1098/rspb.2009.0947

Hudlická O; Garnham A; Shiner R; Egginton S Attenuation of changes in capillary fine structure and leukocyte adhesion improves muscle performance following chronic ischaemia in rats. J Physiol 586 4961-4975, 2008
DOI:10.1113/jphysiol.2008.158055
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Ross EA; Freeman S; Zhao Y; Dhanjal TS; Ross EJ; Lax S; Ahmed Z; Hou TZ; Kalia N; Egginton S; Nash G; Watson SP; Frampton J; Buckley CD A novel role for PECAM-1 (CD31) in regulating haematopoietic progenitor cell compartmentalization between the peripheral blood and bone marrow. PLoS One 3 e2338-, 2008
DOI:10.1371/journal.pone.0002338
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Ahmed SK; Williams JL; Drake-Lee A; Egginton S No significant role for angiogenesis in nasal polyposis. Am J Rhinol 22 24-28, 2008
DOI:10.2500/ajr.2008.22.3124
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Jetha KA; Nash GB; Egginton S Cooled neutrophils become deposited in the microcirculation after infusion: A potential mechanism for microvascular disruption following tissue hypothermia JOURNAL OF THERMAL BIOLOGY 33 451-458, 2008
DOI:10.1016/j.jtherbio.2008.08.004

Campbell HA; Fraser KP; Bishop CM; Peck LS; Egginton S Hibernation in an antarctic fish: on ice for winter. PLoS One 3 e1743-, 2008
DOI:10.1371/journal.pone.0001743
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Egginton S In response to "Point:Counterpoint: There is/is not capillary recruitment in active skeletal muscle during exercise". Journal of applied physiology (Bethesda, Md. : 1985) 104 896-, 2008

Facucho-Oliveira JM; Alderson J; Spikings EC; Egginton S; St John JC Mitochondrial DNA replication during differentiation of murine embryonic stem cells. J Cell Sci 120 4025-4034, 2007
DOI:10.1242/jcs.016972
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Campbell HA; Egginton S The vagus nerve mediates cardio-respiratory coupling that changes with metabolic demand in a temperate nototheniod fish. J Exp Biol 210 2472-2480, 2007
DOI:10.1242/jeb.003822
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Jetha KA; Egginton S; Nash GB Changes in the integrin-mediated adhesion of human neutrophils in the cold and after rewarming. Biorheology 44 37-49, 2007
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Campbell HA; Fraser KPP; Peck LS; Bishop CM; Egginton S Life in the fast lane: The free-ranging activity, heart rate and metabolism of an Antarctic fish tracked in temperate waters JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY 349 142-151, 2007
DOI:10.1016/j.jembe.2007.05.009

Deveci D; Egginton S Effects of acute and chronic cooling on cardiorespiratory depression in rodents Journal of Physiological Sciences 57 73-79, 2007
DOI:10.2170/physiolsci.RP005906
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Nash GB; Egginton S Modelling the Effects of the Haemodynamic Environment on Endothelial Cell Responses Relevant to Angiogenesis In Angiogenesis Assays: A Critical Appraisal of Current Techniques , 2007
DOI:10.1002/9780470029350.ch5
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Taylor EW; Campbell HA; Levings JJ; Young MJ; Butler PJ; Egginton S Coupling of the respiratory rhythm in fish with activity in hypobranchial nerves and with heartbeat. Physiol Biochem Zool 79 1000-1009, 2006
DOI:10.1086/507663
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Milkiewicz M; Hudlicka O; Shiner R; Egginton S; Brown MD Vascular endothelial growth factor mRNA and protein do not change in parallel during non-inflammatory skeletal muscle ischaemia in rat. J Physiol 577 671-678, 2006
DOI:10.1113/jphysiol.2006.113357
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Hauton D; Richards SB; Egginton S The role of the liver in lipid metabolism during cold acclimation in non-hibernator rodents. Comp Biochem Physiol B Biochem Mol Biol 144 372-381, 2006
DOI:10.1016/j.cbpb.2006.03.013
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Campbell HA; Klepacki JZ; Egginton S A new method in applying power spectral statistics to examine cardio-respiratory interactions in fish. J Theor Biol 241 410-419, 2006
DOI:10.1016/j.jtbi.2005.12.005
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Williams JL; Weichert A; Zakrzewicz A; Da Silva-Azevedo L; Pries AR; Baum O; Egginton S Differential gene and protein expression in abluminal sprouting and intraluminal splitting forms of angiogenesis. Clin Sci (Lond) 110 587-595, 2006
DOI:10.1042/CS20050185
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Williams JL; Cartland D; Hussain A; Egginton S A differential role for nitric oxide in two forms of physiological angiogenesis in mouse. J Physiol 570 445-454, 2006
DOI:10.1113/jphysiol.2005.095596
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Whiteley NM; Christiansen JS; Egginton S Polar cod, Boreogadus saida (Gadidae), show an intermediate stress response between Antarctic and temperate fishes Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology 145 493-501, 2006
DOI:10.1016/j.cbpa.2006.08.023
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Degens H; Deveci D; Botto-Van Bemden A; Hoofd LJC; Egginton S Maintenance of heterogeneity of capillary spacing is essential for adequate oxygenation in the soleus muscle of the growing rat Microcirculation 13 467-476, 2006
DOI:10.1080/10739680600776286
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Campbell HA; Leite CAC; Wang T; Skals M; Abe AS; Taylor EW; Egginton S; Rantin FT; Bishop CM Evidence for a respiratory component, similar to mammalian respiratory sinus arrhythmia, in the heart rate variability signal from the rattlesnake, Crotalus durissus terrificus Journal of Experimental Biology 209 2628-2636, 2006
DOI:10.1242/jeb.02278
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Egginton S; Campbell H; Davison W Cardiovascular control in Antarctic fish Deep-Sea Research Part II: Topical Studies in Oceanography 53 1115-1130, 2006
DOI:10.1016/j.dsr2.2006.03.007
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Williams JL; Cartland D; Rudge JS; Egginton S VEGF trap abolishes shear stress- and overload-dependent angiogenesis in skeletal muscle. Microcirculation 13 499-509, 2006
DOI:10.1080/10739680600785717
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Ramsden JD; Buchanan MA; Egginton S; Watkinson JC; Mautner V; Eggo MC Complete inhibition of goiter in mice requires combined gene therapy modification of angiopoietin, vascular endothelial growth factor, and fibroblast growth factor signaling. Endocrinology 146 2895-2902, 2005
DOI:10.1210/en.2005-0168
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Sänger AM; Davison W; Egginton S Muscle fine structure reflects ecotype in two nototheniids Journal of Fish Biology 66 1371-1386, 2005
DOI:10.1111/j.1095-8649.2005.00689.x
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Campbell HA; Taylor EW; Egginton S Does respiratory sinus arrhythmia occur in fishes? Biol Lett 1 484-487, 2005
DOI:10.1098/rsbl.2005.0365
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Campbell HA; Bishop CM; Davies DA; Egginton S Recording long-term heart rate in Paranotothenia angustata using an electronic datalogger JOURNAL OF FISH BIOLOGY 67 1150-1156, 2005
DOI:10.1111/j.1095-8649.2005.00793.x

McKenzie DJ; Wong S; Randall DJ; Egginton S; Taylor EW; Farrell AP The effects of sustained exercise and hypoxia upon oxygen tensions in the red muscle of rainbow trout. J Exp Biol 207 3629-3637, 2004
DOI:10.1242/jeb.01199
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Milkiewicz M; Pugh CW; Egginton S Inhibition of endogenous HIF inactivation induces angiogenesis in ischaemic skeletal muscles of mice. J Physiol 560 21-26, 2004
DOI:10.1113/jphysiol.2004.069757
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Sabharwal R; Johns EJ; Egginton S The influence of acute hypothermia on renal function of anaesthetized euthermic and acclimatized rats. Exp Physiol 89 455-463, 2004
DOI:10.1113/expphysiol.2004.027904
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Sabharwal R; Coote JH; Johns EJ; Egginton S Effect of hypothermia on baroreflex control of heart rate and renal sympathetic nerve activity in anaesthetized rats. J Physiol 557 247-259, 2004
DOI:10.1113/jphysiol.2003.059444
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Campbell HA; Taylor EW; Egginton S The use of power spectral analysis to determine cardiorespiratory control in the short-horned sculpin Myoxocephalus scorpius Journal of Experimental Biology 207 1969-1976, 2004
DOI:10.1242/jeb.00972
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Badr I; Brown MD; Egginton S; Hudlická O; Milkiewicz M; Verhaeg J Differences in local environment determine the site of physiological angiogenesis in rat skeletal muscle. Exp Physiol 88 565-568, 2003
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Jetha KA; Egginton S; Nash GB Increased resistance of neutrophils to deformation upon cooling and rate of recovery on rewarming. Biorheology 40 567-576, 2003
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Milkiewicz M; Hudlicka O; Verhaeg J; Egginton S; Brown MD Differential expression of Flk-I and Flt-I in rat skeletal muscle in response to chronic ischaemia: favourable effect of muscle activity CLINICAL SCIENCE 105 473-482, 2003
DOI:10.1042/CS20030035

Egginton S; Gerritsen M Lumen formation: in vivo versus in vitro observations. Microcirculation 10 45-61, 2003
DOI:10.1038/sj.mn.7800174
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Deveci D; Egginton S Cold exposure differentially stimulates angiogenesis in glycolytic and oxidative muscles of rats and hamsters Experimental Physiology 88 741-746, 2003
DOI:10.1113/eph8802630
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Hudlicka O; Graciotti L; Fulgenzi G; Brown MD; Egginton S; Milkiewicz M; Granata AL The effect of chronic skeletal muscle stimulation on capillary growth in the rat: are sensory nerve fibres involved? JOURNAL OF PHYSIOLOGY-LONDON 546 813-822, 2003
DOI:10.1113/jphysiol.2002.030569

O'Brien KM; Skilbeck C; Sidell BD; Egginton S Muscle fine structure may maintain the function of oxidative fibres in haemoglobinless Antarctic fishes JOURNAL OF EXPERIMENTAL BIOLOGY 206 411-421, 2003
DOI:10.1242/jeb.00088

Egginton S Temperature and angiogenesis: the possible role of mechanical factors in capillary growth. Comp Biochem Physiol A Mol Integr Physiol 132 773-787, 2002
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Deveci D; Egginton S The effects of reduced temperature and photoperiod on body composition in hibernator and non-hibernator rodents Journal of Thermal Biology 27 467-478, 2002
DOI:10.1016/S0306-4565(02)00019-0
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Rivilis I; Milkiewicz M; Boyd P; Goldstein J; Brown MD; Egginton S; Hansen FM; Hudlicka O; Haas TL Differential involvement of MMP-2 and VEGF during muscle stretch-versus shear stress-induced angiogenesis AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 283 H1430-H1438, 2002
DOI:10.1152/ajpheart.00082.2002

Deveci D; Egginton S Differing mechanisms of cold-induced changes in capillary supply in m. tibialis anterior of rats and hamsters Journal of Experimental Biology 205 829-840, 2002
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Egginton S; Skilbeck C; Hoofd L; Calvo J; Johnston IA Peripheral oxygen transport in skeletal muscle of Antarctic and sub-Antarctic notothenioid fish Journal of Experimental Biology 205 769-779, 2002
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Deveci D; Egginton S Muscle ischaemia in rats may be relieved by overload-induced angiogenesis Experimental Physiology 87 479-488, 2002
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Deveci D; Marshall JM; Egginton S Chronic hypoxia induces prolonged angiogenesis in skeletal muscles of rat Experimental Physiology 87 287-291, 2002
DOI:10.1113/eph8702377
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Egginton S; Fairney J; Bratcher J Differential effects of cold exposure on muscle fibre composition and capillary supply in hibernator and non-hibernator rodents. Exp Physiol 86 629-639, 2001
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Milkiewicz M; Brown MD; Egginton S; Hudlicka O Association between shear stress, angiogenesis, and VEGF in skeletal muscles in vivo. Microcirculation 8 229-241, 2001
DOI:10.1038/sj/mn/7800074
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Nash GB; Abbitt KB; Tate K; Jetha KA; Egginton S Changes in the mechanical and adhesive behaviour of human neutrophils on cooling in vitro. Pflugers Arch 442 762-770, 2001
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Egginton S; Zhou AL; Brown MD; Hudlická O Unorthodox angiogenesis in skeletal muscle. Cardiovasc Res 49 634-646, 2001
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Milkiewicz M; Brown MD; Egginton S; Hudlicka O Association between shear stress, angiogenesis, and VEGF in skeletal muscles in vivo Microcirculation 8 229-241, 2001
DOI:10.1038/sj.mn.7800074
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Deveci D; Marshall JM; Egginton S Relationship between capillary angiogenesis, fiber type, and fiber size in chronic systemic hypoxia AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 281 H241-H252, 2001

Hansen-Smith F; Egginton S; Zhou A-L; Hudlicka O Growth of arterioles precedes that of capillaries in stretch-induced angiogenesis in skeletal muscle Microvascular Research 62 1-14, 2001
DOI:10.1006/mvre.2001.2308
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Egginton S; Forster ME; Davison W Control of vascular tone in notothenioid fishes is determined by phylogeny, not environmental temperature AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 280 R1197-R1205, 2001

Deveci D; Stone PCW; Egginton S Differential effect of cold acclimation on blood composition in rats and hamsters Journal of Comparative Physiology - B Biochemical, Systemic, and Environmental Physiology 171 135-143, 2001
DOI:10.1007/s003600000156
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Egginton S; Hudlická O Selective long-term electrical stimulation of fast glycolytic fibres increases capillary supply but not oxidative enzyme activity in rat skeletal muscles. Exp Physiol 85 567-573, 2000
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Egginton S; Zhou AL; Brown MD; Hudlická O The role of pericytes in controlling angiogenesis in vivo. Adv Exp Med Biol 476 81-99, 2000
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Haas TL; Milkiewicz M; Davis SJ; Zhou AL; Egginton S; Brown MD; Madri JA; Hudlicka O Matrix metalloproteinase activity is required for activity-induced angiogenesis in rat skeletal muscle AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 279 H1540-H1547, 2000

Egginton S; Cordiner S; Skilbeck C Thermal compensation of peripheral oxygen transport in skeletal muscle of seasonally acclimatized trout American Journal of Physiology - Regulatory Integrative and Comparative Physiology 279 R375-R388, 2000
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Hawker MJ; Egginton S The effect of stimulation frequency on blood flow in rat fast skeletal muscles. Exp Physiol 84 941-946, 1999
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Deveci D; Egginton S Development of the fluorescent microsphere technique for quantifying regional blood flow in small mammals. Exp Physiol 84 615-630, 1999
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Egginton S; Hudlická O Early changes in performance, blood flow and capillary fine structure in rat fast muscles induced by electrical stimulation. J Physiol 515 ( Pt 1) 265-275, 1999
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Whiteley NM; Egginton S Antarctic fishes have a limited capacity for catecholamine synthesis Journal of Experimental Biology 202 3623-3629, 1999
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Taylor SE; Egginton S; Taylor EW; Franklin CE; Johnston IA Estimation of intracellular pH in muscle of fishes from different thermal environments JOURNAL OF THERMAL BIOLOGY 24 199-208, 1999
DOI:10.1016/S0306-4565(99)00013-3

Egginton S The influence of environmental temperature on microvascular development in fish Zoology 102 164-172, 1999
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Brown MD; Walter H; Hansen-Smith FM; Hudlická O; Egginton S Lack of involvement of basic fibroblast growth factor (FGF-2) in capillary growth in skeletal muscles exposed to long-term contractile activity. Angiogenesis 2 81-91, 1998
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Egginton S; Hudlická O; Brown MD; Walter H; Weiss JB; Bate A Capillary growth in relation to blood flow and performance in overloaded rat skeletal muscle. J Appl Physiol (1985) 85 2025-2032, 1998
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Zhou AL; Egginton S; Brown MD; Hudlicka O Capillary growth in overloaded, hypertrophic adult rat skeletal muscle: an ultrastructural study. Anat Rec 252 49-63, 1998
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Bishop CM; Butler PJ; El Haj AJ; Egginton S Comparative development in captive and migratory populations of the barnacle goose. Physiol Zool 71 198-207, 1998
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Zhou A; Egginton S; Hudlická O; Brown MD Internal division of capillaries in rat skeletal muscle in response to chronic vasodilator treatment with alpha1-antagonist prazosin. Cell Tissue Res 293 293-303, 1998
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Hansen-Smith F; Egginton S; Hudlicka O Growth of arterioles in chronically stimulated adult rat skeletal muscle Microcirculation 5 49-59, 1998
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Moerland TS; Egginton S Intracellular pH of muscle and temperature: Insight from in vivo P NMR measurements in a stenothermal antarctic teleost (Harpagifer antarcticus) Journal of Thermal Biology 23 275-282, 1998
DOI:10.1016/S0306-4565(98)00016-3
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Tuurala H; Egginton S; Soivio A Cold exposure increases branchial water-blood barrier thickness in the eel JOURNAL OF FISH BIOLOGY 53 451-455, 1998
DOI:10.1006/jfbi.1998.0712

Egginton S Anatomical adaptations for peripheral oxygen transport at high and low temperatures South African Journal of Zoology 33 119-128, 1998
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Brown MD; Hudlicka O; Egginton S; Hansen-Smith F Sequence of vascular growth induced by intense activity in rat skeletal muscle, 1998

Ahmed SK; Egginton S; Jakeman PM; Mannion AF; Ross HF Is human skeletal muscle capillary supply modelled according to fibre size or fibre type? Exp Physiol 82 231-234, 1997
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Cordiner S; Egginton S Effects of seasonal temperature acclimatization on muscle metabolism in rainbow trout, Oncorhynchus mykiss Fish Physiology and Biochemistry 16 333-343, 1997
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Egginton S Control of tissue blood flow at very low temperatures Journal of Thermal Biology 22 403-407, 1997
DOI:10.1016/S0306-4565(97)00059-4
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Zhou AL; Egginton S; Hudlicka O Ultrastructural study of three types of physiological angiogenesis in adult rat skeletal muscle. FASEB JOURNAL 11 370-370, 1997

Egginton S; Cordiner S Cold-induced angiogenesis in seasonally acclimatized rainbow trout (Oncorhynchus Mykiss) Journal of Experimental Biology 200 2263-2268, 1997
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Hoofd L; Egginton S The possible role of intracellular lipid in determining oxygen delivery to fish skeletal muscle Respiration Physiology 107 191-202, 1997
DOI:10.1016/S0034-5687(96)02519-4
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Egginton S A comparison of the response to induced exercise in red- and white-blooded Antarctic fishes Journal of Comparative Physiology - B Biochemical, Systemic, and Environmental Physiology 167 129-134, 1997
DOI:10.1007/s003600050056
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Egginton S The physiological response of Antarctic fishes to environmental and experimental stress Cybium 21 415-421, 1997
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Thomson IA; Egginton S; Simms MH; Hudlická O Effect of muscle ischaemia and iloprost during femorodistal reconstruction on capillary endothelial swelling. Int J Microcirc Clin Exp 16 284-290, 1996
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Brown MD; Egginton S; Hudlicka O; Zhou AL Appearance of the capillary endothelial glycocalyx in chronically stimulated rat skeletal muscles in relation to angiogenesis. Exp Physiol 81 1043-1046, 1996
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Lecklin T; Egginton S; Nash GB Effect of temperature on the resistance of individual red blood cells to flow through capillary-sized apertures. Pflugers Arch 432 753-759, 1996
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Egginton S; Hudlicka O; Brown MD; Graciotti L; Granata AL In vivo pericyte-endothelial cell interaction during angiogenesis in adult cardiac and skeletal muscle. Microvasc Res 51 213-228, 1996
DOI:10.1006/mvre.1996.0022
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Hansen-Smith FM; Hudlicka O; Egginton S In vivo angiogenesis in adult rat skeletal muscle: Early changes in capillary network architecture and ultrastructure Cell and Tissue Research 286 123-136, 1996
DOI:10.1007/s004410050681
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Egginton S Effect of temperature on the optimal substrate forβ-oxidation Journal of Fish Biology 49 753-758, 1996
DOI:10.1006/jfbi.1996.0206
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Bishop CM; Butler PJ; El Haj AJ; Egginton S; Loonen MJJE The morphological development of the locomotor and cardiac muscles of the migratory barnacle goose (Branta leucopsis) Journal of Zoology 239 1-15, 1996
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Taylor SE; Egginton S; Taylor EW Seasonal temperature acclimatisation of rainbow trout: Cardiovascular and morphometric influences on maximal sustainable exercise level JOURNAL OF EXPERIMENTAL BIOLOGY 199 835-845, 1996

Egginton S Blood rheology of Antarctic fishes: Viscosity adaptations at very low temperatures Journal of Fish Biology 48 513-521, 1996
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Egginton S; Cordiner S Effect of fixation protocols on muscle preservation and in situ diffusion distances Journal of Fish Biology 47 59-69, 1995
DOI:10.1006/jfbi.1995.0111

BISHOP C; BUTLER P; EGGINTON S; ELHAJ A; GABRIELSEN G DEVELOPMENT OF METABOLIC ENZYME-ACTIVITY IN LOCOMOTOR AND CARDIAC MUSCLES OF THE MIGRATORY BARNACLE GOOSE AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 269 R64-R72, 1995

Lecklin T; Nash G; Egginton S Do fish acclimated to low temperature improve microcirculatory perfusion by adapting red cell rheology? J Exp Biol 198 1801-1808, 1995
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Hudlicka O; Brown MD; Egginton S; Dawson JM Effect of long-term electrical stimulation on vascular supply and fatigue in chronically ischemic muscles. J Appl Physiol (1985) 77 1317-1324, 1994
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Thomson IA; Egginton S; Hudlická O; Sims MH Iloprost reduces leukocyte adhesion in skeletal muscle venules following ischaemia in a rat model of femorodistal bypass. Eur J Vasc Surg 8 335-341, 1994
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Hudlicka O; Egginton S; Brown MD; Okyayuz-Baklouti I Effect of torbafylline on muscle blood flow, performance, and capillary supply in ischemic muscles subjected to varying levels of activity. Can J Physiol Pharmacol 72 811-817, 1994
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Wilson RW; Egginton S Assessment of maximum sustainable swimming performance in rainbow trout (Oncorhynchus mykiss) Journal of Experimental Biology 192 299-305, 1994

Egginton S Stress response in two Antarctic teleosts (Notothenia coriiceps Richardson and Chaenocephalus aceratus Lönnberg) following capture and surgery Journal of Comparative Physiology B 164 482-491, 1994
DOI:10.1007/BF00714586
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HUDLICKA O; EGGINTON S EARLY CHANGES IN MUSCLE BLOOD-FLOW AND PERFORMANCE INDUCED BY CHRONIC ELECTRICAL-STIMULATION OF RAT FAST MUSCLES, 1994

Egginton S; Hudlicka O; Glover M Fine structure of capillaries in ischaemic and non ischaemic rat striated muscle. Effect of torbafylline. Int J Microcirc Clin Exp 12 33-44, 1993
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Nash GB; Egginton S Comparative rheology of human and trout red blood cells. J Exp Biol 174 109-122, 1993
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Egginton S; Hudlicka O Regional capillary perfusion in muscles with limited blood supply: effects of torbafylline. Pflugers Arch 421 336-342, 1992
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Hudlicka O; Brown M; Egginton S Angiogenesis in skeletal and cardiac muscle. Physiol Rev 72 369-417, 1992

Egginton S; Fisher AC; Nash GB Comparative studies on thermal sensitivity of haemorheology; Use of human and fish red blood cells Clinical Hemorheology 12 677-687, 1992

EGGINTON S ADAPTABILITY OF THE ANATOMICAL CAPILLARY SUPPLY TO SKELETAL-MUSCLE OF FISHES JOURNAL OF ZOOLOGY 226 691-698, 1992

Egginton S; Hudlická O The effect of torbafylline on enzyme activities in fast and slow muscles with limited blood supply. Comp Biochem Physiol C 99 163-168, 1991
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Egginton S; Taylor EW; Wilson RW; Johnston IA; Moon TW Stress response in the Antarctic teleosts (Notothenia neglecta Nybelin and N. rossii Richardson) Journal of Fish Biology 38 225-235, 1991
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Hargreaves D; Egginton S; Hudlická O Changes in capillary perfusion induced by different patterns of activity in rat skeletal muscle. Microvasc Res 40 14-28, 1990
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Egginton S Numerical and areal density estimates of fibre type composition in a skeletal muscle (rat extensor digitorum longus). J Anat 168 73-80, 1990
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Egginton S; Turek Z Comparative distributions of numerical and areal indices of tissue capillarity. Adv Exp Med Biol 277 161-169, 1990

Hoofd L; Turek Z; Egginton S Concentric oxygen diffusion in tissue with heterogeneous permeability and consumption Advances in Experimental Medicine and Biology 277 13-20, 1990

Egginton S; Ross HF Influence of muscle phenotype on local capillary supply. Adv Exp Med Biol 248 281-291, 1989
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Egginton S; Ross HF Quantifying capillary distribution in four dimensions. Adv Exp Med Biol 248 271-280, 1989
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Turek Z; Olders J; Hoofd L; Egginton S; Kreuzer F; Rakusan K PO2 histograms in various models of tissue oxygenation in skeletal muscle. Advances in Experimental Medicine and Biology 248 227-237, 1989

Egginton S; Sidell BD Thermal acclimation induces adaptive changes in subcellular structure of fish skeletal muscle American Journal of Physiology - Regulatory Integrative and Comparative Physiology 256 1-9, 1989
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Egginton S; Turek Z; Hoofd LJ Differing patterns of capillary distribution in fish and mammalian skeletal muscle. Respir Physiol 74 383-396, 1988
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Brown MD; Egginton S Capillary density and fine structure in rabbit papillary muscles after a high dose of norepinephrine. Microvasc Res 36 1-12, 1988
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Egginton S Effect of inter-animal variation of a nested sampling design for stereological analysis of skeletal muscle Acta Stereologica 7 81-89, 1988
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HUDLICKA O; EGGINTON S; BROWN M CAPILLARY DIFFUSION DISTANCES - THEIR IMPORTANCE FOR CARDIAC AND SKELETAL-MUSCLE PERFORMANCE NEWS IN PHYSIOLOGICAL SCIENCES 3 134-138, 1988

Egginton S Effects of an anabolic hormone on striated muscle growth and performance. Pflugers Arch 410 349-355, 1987
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Egginton S Effects of an anabolic hormone on aerobic capacity of rat striated muscle. Pflugers Arch 410 356-361, 1987
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Egginton S; Turek Z; Hoofd L Morphometric analysis of sparse capillary networks. Adv Exp Med Biol 215 1-12, 1987
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Egginton S Metamorphosis of the American eel, Anguilla rostrata LeSeur: III. Contractile characteristics of skeletal muscle. Journal of Experimental Zoology 243 39-50, 1987
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Egginton S Is this science? Nature 321 806-806, 1986
DOI:10.1038/321806b0

Egginton S Metamorphosis of the American eel, Anguilla rostrata LeSeur: I. Changes in metabolism of skeletal muscle. The Journal of experimental zoology 237 173-184, 1986
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Egginton S Metamorphosis of the American eel, Anguilla rostrata Le Seur: II. Structural reorganisation of the locomotory musculature Journal of Experimental Zoology 238 297-309, 1986

Egginton S; Johnston IA Effects of acclimation temperature on routine metabolism muscle mitrochondrial volume density and capillary supply in the elver (Anguilla anguilla L.) Journal of Thermal Biology 9 165-170, 1984
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Egginton S; Johnston IA An estimate of capillary anisotropy and determination of surface and volume densities of capillaries in skeletal muscles of the conger eel (Conger conger L.) Quarterly Journal of Experimental Physiology 68 603-617, 1983
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Egginton S; Johnston IA A morphometric analysis of regional differences in myotomal muscle ultrastructure in the juvenile eel (Anguilla anguilla L.) Cell and Tissue Research 222 579-596, 1982

Egginton S; Johnston IA Muscle fibre differentiation and vascularisation in the juvenile European eel (Anguilla anguilla L.) Cell and Tissue Research 222 563-577, 1982
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