Faculty of Biological Sciences

Dr Andrew Cuming

BA, Oxford; PhD 1976, Cambridge.
Senior Lecturer
School of Biology

Contact:  Miall 9.23, +44(0) 113 34 33096, email address for  

You can read more about Dr Cuming's interests here:
www.plants.leeds.ac.uk/people/groups_cum.php

Research Interests

Embryogenesis; Plant development; Gene targeting

Faculty Research and Innovation



Studentship information

Postgraduate studentship areas:

  • Plant development and functional genomics

See also:

Modules managed

BLGY1232 - Introduction to Genetics
BLGY3110 - Applied Genetics

Modules taught

BIOL5294M - MSc Bioscience Research Project Proposal
BIOL5392M - Bioscience MSc Research Project
BLGY1125 - Biology Practicals and Data Analysis
BLGY1232 - Introduction to Genetics
BLGY1234 - Practical Genetics
BLGY1303 - Tutorials for Biology and Genetics
BLGY2100 - Enhanced Study Skills for Biologists
BLGY3021 - Research Project
BLGY3110 - Applied Genetics
BLGY3291 - Comparative Genomics
BLGY3340 - Biology Research Projects

Committees

Member of Undergraduate School Taught Student Education Committee (Programme Manager: Genetics)

Centre membership: The Centre for Plant Sciences

Group Leader Dr Andrew Cuming  (Senior Lecturer)

Embryogenesis; Plant development; Gene targeting 

Dr Sophia Ahmed  (Research Fellow in Precision Medicine)

Evolution of U and V sex chromosomes 

Postgraduates

Daniel Shaw (Co-supervisor) 10% FTE

Chater CC, Caine RS, Tomek M, Wallace S, Kamisugi Y, Cuming AC, Lang D, MacAlister CA, Casson S, Bergmann DC, Decker EL, Frank W, Gray JE, Fleming A, Reski R, Beerling DJ Origin and function of stomata in the moss Physcomitrella patens Nature Plants 2 -, 2016
DOI:10.1038/nplants.2016.179

Cuming AC Gene tagging in Physcomitrella patens : an addition to the genetic toolbox New Phytologist 212 543-545, 2016
DOI:10.1111/nph.14201

Caine RS, Chater CC, Kamisugi Y, Cuming AC, Beerling DJ, Gray JE, Fleming AJ An ancestral stomatal patterning module revealed in the non-vascular land plant Physcomitrella patens Development 143 3306-3314, 2016
DOI:10.1242/dev.135038
View abstract

Kamisugi Y, Whitaker JW, Cuming AC The transcriptional response to DNADouble-strand breaks in Physcomitrella patens PLoS ONE 11 -, 2016
DOI:10.1371/journal.pone.0161204

Stevenson SR, Kamisugi Y, Trinh CH, Schmutz J, Jenkins JW, Grimwood J, Muchero W, Tuskan GA, Rensing SA, Lang D, Reski R, Melkonian M, Rothfels CJ, Li F-W, Larsson A, Wong GK-S, Edwards TA, Cuming AC Genetic analysis of Physcomitrella patens identifies ABSCISIC ACID NON-RESPONSIVE, a regulator of ABA responses unique to basal land plants and required for desiccation tolerance Plant Cell 28 1310-1327, 2016
DOI:10.1105/tpc.16.00091
View abstract

Kamisugi Y, Mitsuya S, El-Shami M, Knight CD, Cuming AC, Baker A Giant peroxisomes in a moss (Physcomitrella patens) peroxisomal biogenesis factor 11 mutant New Phytologist 209 576-589, 2016
DOI:10.1111/nph.13739

McDaniel SF, Perroud PF, Cuming AC, Szövényi P The Ceratodon purpureus Transcriptome Ushers in the Era of Moss Comparative Genomics, 2016
DOI:10.1016/bs.abr.2016.02.003

Wallace S, Chater CC, Kamisugi Y, Cuming AC, Wellman CH, Beerling DJ, Fleming AJ Conservation of Male Sterility 2 function during spore and pollen wall development supports an evolutionarily early recruitment of a core component in the sporopollenin biosynthetic pathway. New Phytol 205 390-401, 2015
DOI:10.1111/nph.13012
View abstract

Charlot F, Chelysheva L, Kamisugi Y, Vrielynck N, Guyon A, Epert A, Le Guin S, Schaefer DG, Cuming AC, Grelon M, Nogué F RAD51B plays an essential role during somatic and meiotic recombination in Physcomitrella Nucleic Acids Research 42 11965-11978, 2014
DOI:10.1093/nar/gku890
View abstract

Szövényi P, Perroud P-F, Symeonidi A, Stevenson S, Quatrano RS, Rensing SA, Cuming AC, Mcdaniel SF De novo assembly and comparative analysis of the Ceratodon purpureus transcriptome Molecular Ecology Resources -, 2014
DOI:10.1111/1755-0998.12284
View abstract

Cove DJ, Cuming AC Genetics and Genomics of Moss Models: Physiology Enters the Twenty-first Century PHOTOSYNTHESIS IN BRYOPHYTES AND EARLY LAND PLANTS 37 187-199, 2014
DOI:10.1007/978-94-007-6988-5_11

Kamisugi Y, Schaefer DG, Kozak J, Charlot F, Vrielynck N, Holá M, Angelis KJ, Cuming AC, Nogué F MRE11 and RAD50, but not NBS1, are essential for gene targeting in the moss Physcomitrella patens. Nucleic Acids Res 40 3496-3510, 2012
DOI:10.1093/nar/gkr1272
View abstract

Chater C, Kamisugi Y, Movahedi M, Fleming A, Cuming AC, Gray JE, Beerling DJ Regulatory Mechanism Controlling Stomatal Behavior Conserved across 400 Million Years of Land Plant Evolution CURR BIOL 21 1025-1029, 2011
DOI:10.1016/j.cub.2011.04.032

Hooper EJ, Duckett JG, Cuming AC, Kunin WE, Pressel S Ephemerella readeri Mull. Hal. (Physcomitrella readeri (Mull. Hal.) I.G. Stone&G.A.M. Scott, Funariidae, Bryophyta): a genus and species new to Europe J BRYOL 32 256-264, 2010
DOI:10.1179/037366810X12814321877589

Caliskan M, Bashiardes S, Cuming AC A plasma membrane H(+)ATPase gene is germination-induced in wheat embryos AFR J BIOTECHNOL 9 268-272, 2010

Fraile-Escanciano A, Kamisugi Y, Cuming AC, Rodriguez-Navarro A, Benito B The SOS1 transporter of Physcomitrella patens mediates sodium efflux in planta NEW PHYTOL 188 750-761, 2010
DOI:10.1111/j.1469-8137.2010.03405.x

Cuming AC Moss as a model system for plant stress responses In Plant Stress Biology: From Genomics To Systems Biology , 2009

Cuming AC Mosses as Model Organisms for Developmental, Cellular and Molecular Biology In Bryophyte Biology , 2009

Cuming AC Plant-pathogen interactions: a view from the evolutionary basement NEW PHYTOL 183 237-239, 2009

Kamisugi Y, Cuming AC Gene targeting In The moss Physcomitrella , 2009
View abstract

Kamisugi Y, von Stackelberg M, Lang D, Care M, Reski R, Rensing SA, Cuming AC A sequence-anchored genetic linkage map for the moss, Physcomitrella patens PLANT J 56 855-866, 2008
DOI:10.1111/j.1365-313X.2008.03637.x

Rensing SA, Lang D, Zimmer AD, Terry A, Salamov A, Shapiro H, Nishiyama T, Perroud PF, Lindquist EA, Kamisugi Y, Tanahashi T, Sakakibara K, Fujita T, Oishi K, Shin-I T, Kuroki Y, Toyoda A, Suzuki Y, Hashimoto S, Yamaguchi K, Sugano S, Kohara Y, Fujiyama A, Anterola A, Aoki S, Ashton N, Barbazuk WB, Barker E, Bennetzen JL, Blankenship R, Cho SH, Dutcher SK, Estelle M, Fawcett JA, Gundlach H, Hanada K, Heyl A, Hicks KA, Hughes J, Lohr M, Mayer K, Melkozernov A, Murata T, Nelson DR, Pils B, Prigge M, Reiss B, Renner T, Rombauts S, Rushton PJ, Sanderfoot A, Schween G, Shiu SH, Stueber K, Theodoulou FL, Tu H, Van de Peer Y, Verrier PJ, Waters E, Wood A, Yang LX, Cove D, Cuming AC, Hasebe M, Lucas S, Mishler BD, Reski R, Grigoriev IV, Quatrano RS, Boore JL The Physcomitrella genome reveals evolutionary insights into the conquest of land by plants SCIENCE 319 64-69, 2008
DOI:10.1126/science.1150646

Cuming AC, Cho SH, Kamisugi Y, Graham H, Quatrano RS Microarray analysis of transcriptional responses to abscisic acid and osmotic, salt, and drought stress in the moss, Physcomitrella patens NEW PHYTOL 176 275-287, 2007
DOI:10.1111/j.1469-8137.2007.02187.x

Kamisugi Y, Schlink K, Rensing SA, Schween G, von Stackelberg M, Cuming AC, Reski R, Cove DJ The mechanism of gene targeting in Physcomitrella patens: homologous recombination, concatenation and multiple integration NUCLEIC ACIDS RES 34 6205-6214, 2006
DOI:10.1093/nar/gkl832

Kamisugi Y, Cuming AC The evolution of the abscisic acid-response in land plants: comparative analysis of group 1 LEA gene expression in moss and cereals PLANT MOL BIOL 59 723-737, 2005
DOI:10.1007/s11103-005-0909-z

Kamisugi Y, Cuming AC, Cove DJ Parameters determining the efficiency of gene targeting in the moss Physcomitrella patens NUCLEIC ACIDS RES 33 -, 2005
DOI:10.1093/nar/gnil172

Caliskan M, Ozcan B, Turan C, Cuming AC Localization of germin genes and their products in developing wheat coleoptiles J BIOCHEM MOL BIOL 37 339-342, 2004

Caliskan M, Turet M, Cuming AC Formation of wheat (Triticum aestivum L.) embryogenic callus involves peroxide-generating germin-like oxalate oxidase PLANTA 219 132-140, 2004
DOI:10.1007/s00425-003-1199-9

Caliskan M, Turet-Sayin M, Turan C, Cuming AC Identification of germin isoforms in wheat callus CEREAL RES COMMUN 32 355-361, 2004

Caliskan M, Bashiardes S, Ozcan B, Cuming AC Isolation and localization of new germination-related sequences from wheat embryos J BIOCHEM MOL BIOL 36 580-585, 2003

Kamisugi Y, Cuming AC Genomes and databases In New frontiers in bryology– physiology, molecular biology and functional genomics , 2003

Knight CD, Cove DJ, Cuming AC, Quatrano RS Moss Gene Technology In Molecular PlantBiology - a practical approach , 2002

Machuka JS, Bashiardes S, Ruben E, Spooner K, Cuming AC, Knight CD, Cove DJ Sequence analysis of Expressed sequence tags from an ABA-treated cDNA library identifies stress response genes in the moss Physcomitrella patens. Plant and Cell Physiology 40 378-387, 1999

Caliskan M, Cuming AC Spatial specificity of H2O2-generating oxalate oxidase gene expression during wheat embryo germination PLANT J 15 165-171, 1998

ROBERTSON M, CUMING AC, CHANDLER PM SEQUENCE-ANALYSIS AND HORMONAL-REGULATION OF A DEHYDRIN PROMOTER FROM BARLEY, HORDEUM-VULGARE PHYSIOL PLANTARUM 94 470-478, 1995

KNIGHT CD, SEHGAL A, ATWAL K, WALLACE JC, COVE DJ, COATES D, QUATRANO RS, BAHADUR S, STOCKLEY PG, CUMING AC MOLECULAR RESPONSES TO ABSCISIC-ACID AND STRESS ARE CONSERVED BETWEEN MOSS AND CEREALS PLANT CELL 7 499-506, 1995

Robertson M, Cuming AC, Chandler PM Sequence analysis and hormonal regulation of a dehydrin promoter from barley, Hordeum vulgare Physiologia Plantarum 94 470-478, 1995
DOI:10.1111/j.1399-3054.1995.tb00956.x
View abstract

ONDE S, FUTERS TS, CUMING AC RAPID ANALYSIS OF AN OSMOTIC-STRESS RESPONSIVE PROMOTER BY TRANSIENT EXPRESSION IN INTACT WHEAT EMBRYOS J EXP BOT 45 561-566, 1994

Futers TS, Onde S, Turet M, Cuming AC Sequence analysis of two tandemly linked Em genes from wheat. Plant Mol Biol 23 1067-1072, 1993
View abstract

Taylor RM, Cuming AC Selective proteolysis of the wheat Em polypeptide. Identification of an endopeptidase activity in germinating wheat embryos. FEBS Lett 331 71-75, 1993
View abstract

Taylor RM, Cuming AC Purification of an endoproteinase that digests the wheat 'Em' protein in vitro, and determination of its cleavage sites. FEBS Lett 331 76-80, 1993
View abstract

LANE BG, DUNWELL JM, RAY JA, SCHMITT MR, CUMING AC GERMIN, A PROTEIN MARKER OF EARLY PLANT DEVELOPMENT, IS AN OXALATE OXIDASE J BIOL CHEM 268 12239-12242, 1993

BUTLER WM, CUMING AC DIFFERENTIAL MOLECULAR RESPONSES TO ABSCISIC-ACID AND OSMOTIC-STRESS IN VIVIPAROUS MAIZE EMBRYOS PLANTA 189 47-54, 1993

Lane BG, Cuming AC, Frégeau J, Carpita NC, Hurkman WJ, Bernier F, Dratewka-Kos E, Kennedy TD Germin isoforms are discrete temporal markers of wheat development. Pseudogermin is a uniquely thermostable water-soluble oligomeric protein in ungerminated embryos and like germin in germinated embryos, it is incorporated into cell walls. Eur J Biochem 209 961-969, 1992
View abstract

Morris PC, Kumar A, Bowles DJ, Cuming AC Osmotic stress and abscisic acid induce expression of the wheat Em genes. Eur J Biochem 190 625-630, 1990
View abstract

FUTERS TS, VAUGHAN TJ, SHARP PJ, CUMING AC MOLECULAR-CLONING AND CHROMOSOMAL LOCATION OF GENES ENCODING THE EARLY-METHIONINE-LABELED (EM) POLYPEPTIDE OF TRITICUM-AESTIVUM L VAR CHINESE SPRING THEOR APPL GENET 80 43-48, 1990

WILLIAMSON JD, QUATRANO RS, CUMING AC EM POLYPEPTIDE AND ITS MESSENGER-RNA LEVELS ARE MODULATED BY ABSCISIC-ACID DURING EMBRYOGENESIS IN WHEAT EUR J BIOCHEM 152 501-507, 1985

CUMING AC DEVELOPMENTAL REGULATION OF GENE-EXPRESSION IN WHEAT EMBRYOS - MOLECULAR-CLONING OF A DNA-SEQUENCE ENCODING THE EARLY METHIONINE-LABELED (EM) POLYPEPTIDE EUR J BIOCHEM 145 351-357, 1984

CUMING AC CONTROL OF RIBOSOMAL-PROTEIN SYNTHESIS DURING WHEAT EMBRYO INBIBITION BIOCHIM BIOPHYS ACTA 783 42-52, 1984

CUMING AC, BENNETT J BIOSYNTHESIS OF THE LIGHT-HARVESTING CHLOROPHYLL A-B PROTEIN - CONTROL OF MESSENGER-RNA ACTIVITY BY LIGHT EUR J BIOCHEM 118 71-80, 1981

CUMING AC, KENNEDY TD, LANE BG WHEAT EMBRYO RIBONUCLEATES .14. MASS ISOLATION OF MESSENGER-RNA FROM WHEAT-GERM AND COMPARISON OF ITS TRANSLATIONAL CAPACITY WITH THAT OF MESSENGER-RNA FROM IMBIBING WHEAT EMBRYOS CAN J BIOCHEM CELL B 57 1170-1175, 1979

CUMING AC, LANE BG PROTEIN-SYNTHESIS IN IMBIBING WHEAT EMBRYOS EUR J BIOCHEM 99 217-224, 1979

CUMING AC, LANE BG WHEAT EMBRYO RIBONUCLEATES .11. CONSERVED MESSENGER-RNA IN DRY WHEAT EMBRYOS AND ITS RELATION TO PROTEIN-SYNTHESIS DURING EARLY IMBIBITION CAN J BIOCHEM CELL B 56 365-&, 1978

CUMING AC, OSBORNE DJ MEMBRANE TURNOVER IN IMBIBED AND DORMANT EMBRYOS OF WILD OAT (AVENA-FATUA L) .1. PROTEIN TURNOVER AND MEMBRANE REPLACEMENT PLANTA 139 209-217, 1978

CUMING AC, OSBORNE DJ MEMBRANE TURNOVER IN IMBIBED DORMANT EMBRYOS OF WILD OAT (AVENA-FATUA L) .2. PHOSPHOLIPID TURNOVER AND MEMBRANE REPLACEMENT PLANTA 139 219-226, 1978

Cross LL, Paudyal R, Kamisugi Y, Berry A, Cuming AC, Baker A, Warriner SL Towards designer organelles by subverting the peroxisomal import pathway Nature Communications -,