Faculty of Biological Sciences

Recent Publications

2009 |2008 |2007 | 2006 | 2005 | 2004 | 2003 | 2002

2009:

Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants.
(2009) Diabetes 58, 2070-2083.
Nicolson, T.J., Bellomo1, E.A., Wijesekara, N., Loder, M.K., Baldwin, J.M., Gyulkhandanyan, A.V., Koshkin, V., Tarasov, A.I., Carzaniga, R., Kronenberger, K., Taneja, T.K., da Silva Xavier, G., Libert, S., Froguel, P., Scharfmann R., Stetsyuk, V., Ravassard, P., Parker, H., Gribble, F.M., Reimann, F., Sladek, R., Hughes, S.J., Johnson, P.R.V., Masseboeuf, M., Burcelin, R., Baldwin, S.A., Liu, M., Lara-Lemus, R., Arvan, P., Schuit, F.C., Wheeler, M.B., Chimienti, F. and Rutter, G.A.
click here to read abstract

Conserved glutamate residues E343 and E519 provide mechanistic insights into human concentrative nucleoside transporter 3 (hCNT3) structure and function.
(2009) J. Biol. Chem. 284, 17266-17280.
Slugoski, M.D., Smith, K.M., Ng, A.M.L., Yao, S.Y.M., Karpinski, E., Cass, C.E., Baldwin, S.A. and Young, J.D.
click here to read abstract

Substituted cysteine accessibility method (SCAM) analysis of human concentrative nucleoside transporter hCNT3 reveals a novel discontinuous region of functional importance within the CNT family motif (G/A)XKX3NEFVA(Y/M/F).
(2009) J. Biol. Chem. 284, 17281-17292.
Slugoski, M.D., Ng, A.M., Yao, S.Y., Lin, C.C., Mulinta, R., Cass, C.E., Baldwin, S.A. and Young, J.D.
click here to read abstract

Transepithelial fluxes of adenosine and 2'-deoxyadenosine across human renal proximal tubule cells: the roles of nucleoside transporters hENT1, hENT2, and hCNT3.
(2009) Am. J. Physiol. 296, F1439- F1451.
Elwi, A.N., Damaraju, V.L., Kuzma, M.L., Mowles, D.A., Baldwin, S.A., Young, J.D., Sawyer, M.B. and Cass, C.E.
click here to read abstract

The sodium-dependent D-glucose transport protein of Helicobacter pylori.
(2009) Mol. Microbiol. 71, 391-403.
Psakis, G., Saidijam, M., Shibayama, K., Polaczek, J., Bettaney, K.E., Baldwin, J.M., Baldwin, S.A., Hope, R., Essen, L.O., Essenberg, R.C. and Henderson, P.J.
click here to read abstract

The NBDs that wouldn't die: A cautionary tale of the use of isolated nucleotide binding domains of ABC transporters.
(2009) Communicative & Integrative Biology. 2, 97-99.
De Marcos Lousa, C., Dietrich, D., Johnson, B., Baldwin, S.A., Holdsworth, M.J., Theodoulou F.L. & Baker A.
click here to read abstract

Mutations in the Arabidopsis Peroxisomal ABC Transporter COMATOSE Allow Differentiation between Multiple Functions in planta: Insights from an Allelic Series.
(2009) Mol. Biol. Cell. 20, 530-543.
Dietrich, D., Schmuths, H., De Marcos, L.C., Baldwin, J.M., Baldwin, S.A., Baker, A., Theodoulou, F.L. & Holdsworth, M.J.
click here to read abstract

Human concentrative nucleoside transporter 3 is a determinant of fludarabine transportability and cytotoxicity in human renal proximal tubule cell cultures.
(2009) Cancer Chemother. Pharmacol. 63, 289-301.
Elwi, A.N., Damaraju, V.L., Kuzma, M.L., Baldwin, S.A., Young, J.D., Sawyer, M.B. & Cass, C.E.
click here to read abstract

2008:

A high-throughput assay of membrane protein stability.
(2008) Mol. Membr. Biol. 25, 617-624.
Postis, V.L., Deacon, S.E., Roach, P.C., Wright, G.S., Xia, X., Ingram, J.C., Hadden, J.M., Henderson, P.J., Phillips, S.E., McPherson, M.J. & Baldwin, S.A.
click here to read abstract

Large-scale preparation of bacterial cell membranes by tangential flow filtration.
(2008) Mol. Membr. Biol. 25, 609-616.
Roach, P.C., Postis, V.L., Deacon, S.E., Wright, G.S., Ingram, J.C., Xia, X., McPherson, M.J. & Baldwin, S.A.
click here to read abstract

Investigation of the structure and function of a Shewanella oneidensis arsenical-resistance family transporter.
(2008) Mol. Membr. Biol. 25, 691-701.
Xia, X., Postis, V.L., Rahman, M., Wright, G.S., Roach, P.C., Deacon, S.E., Ingram, J.C., Henderson, P.J., Findlay, J.B., Phillips, S.E., McPherson, M.J. & Baldwin, S.A.
click here to read abstract

Reliable scale-up of membrane protein over-expression by bacterial auto-induction: from microwell plates to pilot scale fermentations.
(2008) Mol. Membr. Biol. 25, 588-598.
Deacon, S.E., Roach, P.C.J., Postis, V.L.G., Wright, G.S.A., Xia, X., Phillips, S.E.V., Knox, J.P., Henderson, P.J.F., McPherson, M.J. & Baldwin, S.A.
click here to read abstract

Probing metal ion substrate-binding to the E. coli ZitB exporter in native membranes by solid state NMR.
(2008) Mol. Membr. Biol. 25, 683-690.
Rahman, M., Patching, S.G., Ismat, F., Henderson, P.J.F., Herbert, R.B., Baldwin, S.A. & McPherson, M.J.
click here to read abstract

3D Reconstruction of Mammalian Septin Filaments. .
(2008) J. Mol. Biol. 376 , 1-7.
Lukoyanova, N., Baldwin , S.A. & Trinick, J.
click here to read abstract

A proton-mediated conformational shift identifies a mobile pore-lining cysteine residue (C561) in human concentrative nucleoside transporter 3 (hCNT3).
(2008) J. Biol. Chem. 283 , 8496-8507.
Slugoski, M.D., Ng, A.M., Yao, S.Y., Smith, K.M., Lin, C.C., Zhang, J., Karpinski, E., Cass, C.E., Baldwin, S.A. & Young, J.D.
click here to read abstract

A rare mutation in ABCC8/SUR1 leading to altered KATP channel activity and β-cell glucose sensing is associated with type 2 diabetes mellitus in adults.
(2008) Diabetes 57, 1595-1604.
Tarasov, A.I., Nicolson, T., Riveline, J.P., Taneja, T.K., Baldwin, S.A., Baldwin, J.M., Charpentier, G., Gautier, J.F., Froguel, P., Vaxillaire, M. & Rutter, G.A
click here to read abstract

Mutation of Trp 29 of human equilibrative nucleoside transporter 1 alters affinity for coronary vasodilator drugs and nucleoside selectivity.
(2008) Biochem. J. 414, 291-300
Paproski, R.J., Visser, F., Zhang, J., Tackaberry, T., Damaraju, V., Baldwin, S.A., Young, J.D. & Cass, C.E.
click here to read abstract

A conformationally mobile cysteine residue (Cys-561) modulates Na+ and H+ activation of human CNT3.
(2008) J. Biol. Chem. 283, 24922-24934.
Slugoski, M.D., Smith, K.M., Mulinta, R., Ng, A.M.L., Yao, S.Y.M., Morrison, E.L., Lee, Q.O.T., Zhang, J., Karpinski, E., Cass, C.E., Baldwin, S.A. and Young, J.D.
click here to read abstract

Relative substrate affinities of wild-type and mutant forms of the Escherichia coli sugar transporter GalP determined by solid-state NMR.
(2008) Mol. Membr. Biol. 25 474-484.
Patching, S.G., Psakis, G., Baldwin, S.A., Baldwin, J., Henderson, P.J. & Middleton, D.A.
click here to read abstract

The ENT family of nucleoside and nucleobase transporter proteins..
(2008) Xenobiotica 38, 995-1021
Young, J.D., Yao, S.Y.M., Sun, L., Cass, C.E. & Baldwin, S.A.
click here to read abstract

 

TOP

2007:

The role of nucleoside transporters in cancer chemotherapy with nucleoside drugs.
(2007) Cancer Metastasis Rev. 26 , 85-110.
Zhang, J., Visser, F., King, K.M., Baldwin, S.A. , Young, J.D. & Cass, C.E.
click here to read abstract

Nucleoside transport as a potential target for chemotherapy in malaria.
(2007) Curr.Pharm.Design 13 , 569-580.
Baldwin , S.A. , McConkey, G.A., Cass, C.E. & Young, J.D.
click here to read abstract

Specific mutations in transmembrane helix 8 of human concentrative Na + /nucleoside cotransporter hCNT1 affect permeant selectivity and cation coupling.
(2007) Biochemistry 46 , 1684-1693.
Slugoski, M.D., Loewen, S.K., Ng, A.M.L., Smith, K.M., Yao, S.Y.M., Karpinski, E., Cass, C.E., Baldwin, S.A. & Young, J.D.
click here to read abstract

Functional and structural characterization of the first prokaryotic member of the lat family: A model for APC transporters.
(2007) J. Biol. Chem. 282, 13270-13281.
Reig, N., del Rio , C., Casagrande, F., Ratera, M., Gelpi, J.L., Torrents, D., Henderson , P.J., Xie, H., Baldwin, S.A. , Zorzano, A., Fotiadis, D. & Palacin, M.
click here to read abstract

Residues 334 and 338 in transmembrane segment 8 of human equilibrative nucleoside transporter 1 are important determinants of inhibitor sensitivity, protein folding and catalytic turnover.
(2007) J. Biol. Chem. 282, 14148-14157.
Visser, F., Sun, L., Damaraju, V., Tackaberry, T., Peng, Y., Robins, M.J., Baldwin, S.A. , Young, J.D. & Cass, C.E.
click here to read abstract

Topology-informed strategies for the overexpression and purification of membrane proteins.
(2007) Mol. Memb. Biol. 24, 407-418
Rahman, M., Ismat, F., McPherson, M.J. & Baldwin , S.A.
click here to read abstract

Localization of broadly selective equilibrative and concentrative nucleoside transporters, hENT1 and hCNT3, in human kidney. (2007) Am. J. Physiol. Renal Physiol. 293, F200-F211.
Damaraju, V.L., Elwi, A.N., Hunter, C., Carpenter, P., Santos, C., Barron, G.M., Sun, X., Baldwin, S.A. , Young, J.D., Mackey, J.R., Sawyer, M.B. & Cass, C.E.
click here to read abstract

Conserved Glutamate Residues Are Critically Involved in Na+/Nucleoside Cotransport by Human Concentrative Nucleoside Transporter 1.
(2007) J. Biol. Chem. 282, 30607-30617.
Yao, S.Y.M., Ng, A.M.L., Slugoski, M.D., Smith, K.M., Mulinta, R., Karpinski, E., Cass, C.E., Baldwin, S.A. & Young, J.D.
click here to read abstract

Cation coupling properties of human concentrative nucleoside transporters hCNT1, hCNT2 and hCNT3 .
(2007) Mol. Membr. Biol . 24, 53-64.
Smith, K.M., Slugoski, M,D., Cass, C.E., Baldwin, S.A ., Karpinski, E. & Young, J.D.
click here to read abstract

The N-terminal Helix Is a Post-assembly Clamp in the Bacterial Outer Membrane Protein PagP.
(2007) J. Mol. Biol. 373 , 529-540.
Huysmans, G.H., Radford, S.E., Brockwell, D.J. & Baldwin, S.A.
click here to read abstract


TOP

2006:

Cysteine accessibility analysis of transmembrane domains 11, 12 and 13 of human concentrative nucleoside transporter 3.
(2006) Biochem. J. 394, 389-398 .
Zhang, J., Tackaberry, T., Ritzel, M.W., Raborn, T., Barron, G., Baldwin, S.A. , Young, J.D. & Cass, C.E.
click here to read abstract

Studies of Nucleoside Transporters Using Novel Autofluorescent Nucleoside Probes.
(2006) Biochemistry 45, 1087-1098.
Zhang, J., Sun, X., Smith, K.M., Carpenter, P., Barron, G., Robins, M.J., Baldwin, S.A. , Young, J.D. & Cass, C.E.
click here to read abstract

Quantitative proteomics reveals post-translational control as a regulatory factor in primary hematopoietic stem cells.
(2006) Blood 107, 4687-4694.
Unwin, R.D., Smith, D.L., Blinco, D., Wilson , C.L., Miller, C.J., Evans , C.A. , Jaworska, E., Baldwin, S.A. , Barnes, K., Pierce, A., Spooncer, E. & Whetton, A.D.
click here to read abstract

Nucleoside transporters: from scavengers to novel therapeutic targets.
(2006) Trends Pharmacol. Sci. 27, 416-425.
King, A.E., Ackley, M.A., Cass, C.E., Young, J.D. & Baldwin, S.A.
click here to read abstract

Characterization of uridine permease, Fui1p, of Saccharomyces cerevisiae: The transport mechanism and permeant-binding profile.
(2006) J. Biol. Chem. 281 , 28210-28221
Zhang, J., Smith, K.M., Tackaberry, T., Sun, X., Carpenter, P., Slugoski, M.D., Robins, M.J., Nielsen, L.P., Nowak, I., Baldwin, S.A., Young, J.D. & Cass, C.E
click here to read abstract

Distribution and Functional Characterisation of ENT4, a Novel Cardiac Adenosine Transporter Activated at Acidic pH.
(2006) Circulation Research. 99 , 510-519.
Barnes, K., Dobrzynski, H., Foppolo, S., Beal, P.R., Ismat, F., Scullion, E.R., Sun, L., Tellez, J., Ritzel, M.W.L., Claycomb, W.C., Cass, C.E., Young, J.D., Billeter-Clark, R., Boyett, M.R., & Baldwin, S.A.
click here to read abstract

Modeling, Docking, and Simulation of the Major Facilitator Superfamily.
(2006) Biophys. J. 91 , L84-6
Holyoake, J., Caulfeild, V., Baldwin, S.A. & Sansom, M.S.P.
click here to read abstract

Renal nucleoside transporters: physiological and clinical implications.
(2006) Biochem Cell Biol. 84 , 844-858
Elwi, A.N., Damaraju, V.L., Baldwin, S.A., Young, J.D., Sawyer, M.B. & Cass, C.E.
click here to read abstract

TOP

2005:

Identification and Functional Characterization of Variants in Human Concentrative Nucleoside Transporter 3, hCNT3 (SLC28A3), arising from Single Nucleotide Polymorphisms in Coding Regions of the hCNT3 Gene.
(2005) Pharmacogenetics and Genomics 15, 173-182.
Damaraju, S., Zhang, J., Visser, F., Tackaberry, T., Dufour, J., Smith, K.M., Slugoski, M., Ritzel, M.W.L., Baldwin, S.A., Young, J.D. & Cass, C.E.
click here to read abstract

Residue 33 of Human Equilibrative Nucleoside Transporter 2 is a Functionally Important Component of Both the Dipyridamole and Nucleoside Binding Sites.
(2005) Mol. Pharmacol. 67, 1291-1298.
Visser, F., Zhang, J., Raborn, R.T., Baldwin, S.A ., Young, J.D. & Cass, C.E.
click here to read abstract

Identification and mutational analysis of amino acid residues involved in dipyridamole interactions with human and Caenorhabditis elegans equilibrative nucleoside transporters.
(2005) J. Biol. Chem .280, 11025-11034.
Visser, F., Baldwin, S.A. , Isaac, R.E., Young, J.D. & Cass, C.E.
click here to read abstract

The nucleoside transport proteins, NupC and NupG, from Escherichia coli : specific structural motifs necessary for the binding of ligands.
(2005) Org. Biomol. Chem. 3, 462-470.
Patching, S.G, Baldwin, S.A. , Baldwin , A.D., Young, J.D., Gallagher, M.P. Henderson, P.J.F. & Herbert, R.B.
click here to read abstract

Adenosine contributes to mu-opioid synaptic inhibition in rat substantia gelatinosa in vitro.
(2005) Neurosci. Lett. 376 102- 106.
Ackley, M.A., Baldwin , S.A. & King, A.E.
click here to read abstract

Functional characterisation of novel human and mouse equilibrative nucleoside transporters (hENT3 and mENT3) located in intracellular membranes.
(2005) J. Biol. Chem. 280, 15880-15887.
Baldwin, S.A. , Yao , S.Y.M, Hyde, R.J., Ng, A.M., Foppolo, S., Barnes, K., Ritzel, M.W., Cass, C.E. & Young, J.D.
click here to read abstract

Chronic myeloid leukaemia: an investigation into the role of Bcr-Abl-induced abnormalities in glucose transport regulation.
(2005) Oncogene 24, 3257-3267.
Barnes, K., McIntosh, E., Whetton, A.D., Daley, G.Q., Bentley, J. & Baldwin , S.A.
click here to read abstract

The broadly selective human Na+/nucleoside cotransporter (hCNT3) exhibits novel cation-coupled nucleoside transport characteristics.
(2005) J. Biol. Chem. 280, 25436-25449.
Smith, K.M., Slugoski, M.D., Loewen, S.K., Ng, A.M., Yao , S.Y., Chen, X.Z., Karpinski, E., Cass, C.E., Baldwin, S.A. & Young, J.D.
click here to read abstract

Mammalian exocyst complex is required for the docking step of insulin vesicle exocytosis.
(2005) J. Biol. Chem.280, 25565-25570.
Tsuboi, T., Ravier, M.A., Xie, H., Ewart, M.A., Gould, G.W., Baldwin, S.A. & Rutter, G.A.
click here to read abstract

Uridine Binding and Transportability Determinants of Human Concentrative Nucleoside Transporters.
(2005)Mol. Pharmacol. 68, 830-839.
Zhang, J., Smith, K.M., Tackaberry, T., Visser, F., Robins, M.J., Nielsen, L.P., Nowak, I. , Karpinski, E., Baldwin, S.A., Young, J.D. & Cass, C.E.
click here to read abstract

Localisation of the NBMPR-sensitive equilibrative nucleoside transporter, ENT1, in the rat dorsal root ganglion and lumbar spinal cord.
(2005) Brain Res. 1059, 129-138 .
Governo, R.J.M., Deuchars, J., Baldwin, S.A . & King, A.E.
click here to read abstract

Polarized distribution of nucleoside transporters in rat brain endothelial and choroid plexus epithelial cells.
(2005) J. Neurochem. 94 , 1420-1426.
Redzic, Z.B., Biringer, J., Barnes, K., Baldwin, S.A. , Al-Sarraf, H., Nicola, P.A., Young, J.D., Cass, C.E., Barrand, M.A. & Hladky, S.B.
click here to read abstract

Rab11-FIP3 and FIP4 interact with Arf6 and the Exocyst to control membrane traffic in cytokinesis.
(2005) EMBO J. 24, 3389-3399.
Fielding, A.B., Schonteich, E., Matheson, J., Wilson, G., Yu, X., Hickson, G.R., Srivastava, S., Baldwin, S.A. , Prekeris, R. & Gould, G.W.
click here to read abstract

TOP

2004:

Transport of physiological nucleosides and anti-viral and anti-neoplastic nucleoside drugs by recombinant Escherichia coli nucleoside-H+ cotransporter (NupC) produced in Xenopus laevis oocytes.
(2004) Mol. Memb. Biol. 21, 1-10.
Loewen, S.K., Yao, S.Y.M., Slugoski, M.D., Mohabir, N.N., Turner, R.J., Mackey, J.R., Weiner, J.H., Gallagher, M.P., Henderson, P.J.F., Baldwin, S.A., Cass, C.E. & Young, J.D.
click here to read abstract

The equilibrative nucleoside transporter family, SLC29.
(2004) Pflugers Arch. - Eur. J. Physiol. 447, 735-743.
Baldwin, S.A., Beal, P.R., Yao, S.Y., King, A.E., Cass, C.E. & Young, J.D.
click here to read abstract

Methyl-β-cyclodextrin stimulates glucose uptake in Clone 9 cells: a possible role for lipid rafts.
(2004) Biochem. J. 378, 343-351.
Barnes, K., Ingram, J.C., Bennett, M.D.M., Stewart, G.W. & Baldwin, S.A.
click here to read abstract

Uridine recognition motifs of human equilibrative nucleoside transporters 1 and 2 produced in Saccharomyces cerevisiae.
(2004) Nucleosides Nucleotides Nucleic Acids 23, 361-373.
Vickers, M.F., Zhang, J., Visser, F., Tackaberry, T., Robins, M.J., Nielsen, L.P., Nowak, I., Baldwin, S.A., Young, J.D. & Cass, C.E.
click here to read abstract

Electrophysiological Characterization of a Recombinant Human Na+-coupled Nucleoside Transporter (hCNT1) Produced in Xenopus Oocytes.
(2004) J. Physiol. 558, 807-23.
Smith, K.M., Ng, A.M.L., Yao, S.Y.M., Labedz, K.A., Knaus, E.E., Wiebe, L.I., Cass, C.E., Baldwin, S.A., Chen, X-Z, Karpinski. E. & Young, J.D.
click here to read abstract

Functional redundancy of two nucleoside transporters of the ENT family (CeENT1, CeENT2) required for development of Caenorhabditis elegans.
(2004) Mol. Memb. Biol. 21 , 247-259.
Appleford, P.J., Griffiths, M., Yao, S.Y.M., Ng, A.M.L., Chomey, E.G., Isaac, R.E., Coates, D., Hope, I.A., Cass, C.E., Young, J.D. & Baldwin, S.A.
click here to read abstract

Allelic isoforms of the H + /nucleoside co-transporter (CaCNT) from Candida albicans reveal separate high- and low-affinity transport systems for nucleosides.
(2004) Yeast 21, 1269-1277.
Slugoski, M.D., Loewen, S.K., Ng, A.M., Baldwin, S.A ., Cass, C.E. & Young, J.D.
click here to read abstract

Purification and properties of the Escherichia coli nucleoside transporter NupG, a paradigm for a major facilitator transporter sub-family.
(2004) Mol. Memb. Biol. 21 , 323-336.
Xie, H., Patching, S.G., Gallagher, M.P., Litherland, G.J., Brough, A.R., Venter, H., Yao, S.Y.M., Ng, A.M.L. Young, J.D., Herbert, R.B., Henderson, P.J.F. & Baldwin, S.A.
click here to read abstract

TOP

2003:

Control of glutamatergic neurotransmission in the rat spinal dorsal horn by the nucleoside transporter ENT1.
(2003) J. Physiol. 548, 507-17.
Ackley, M.A., Governo, R.J., Cass, C.E., Young, J.D., Baldwin, S.A. & King, A.E
click here to read abstract

Coupling of CFTR-mediated anion secretion to nucleoside transporters and adenosine homeostasis in Calu-3 cells.
(2003) J. Membr. Biol. 193, 169-179.
Szkotak, A.J., Ng, A.M.L., Man, S.F.P., Baldwin, S.A., Cass, C.E., Young, J.D. & Duszyk, M.
click here to read abstract

Functional characterization of a H+/nucleoside co-transporter (CaCNT) from Candida albicans, a fungal member of the concentrative nucleoside transporter (CNT) family of membrane proteins.
(2003) Yeast 20, 661-75.
Loewen, S.K., Ng, A.M., Mohabir, N.N., Baldwin, S.A., Cass, C.E. & Young, J.D.
click here to read abstract

Cloning, heterologous expression, and in situ characterization of the first high affinity nucleobase transporter from a protozoan.
(2003) J. Biol. Chem. 278, 23502-23507.
Burchmore, R.J., Wallace, L.J., Candlish, D., Al-Salabi, M.I., Beal, P.R., Barrett, M.P., Baldwin, S.A. & de Koning, H.P.
click here to read abstract

Equilibrative nucleoside transporters of Arabidopsis thaliana: cDNA cloning, expression pattern and analysis of transport activities.
(2003) J. Biol Chem. 278, 35732-35742.
Li, G., Liu, K., Baldwin, S.A. & Wang, D.
click here to read abstract

Constitutive protein secretion from the trans-Golgi network to the plasma membrane.
(2003) Mol. Memb. Biol. 20, 129-139.
Ponnambalam, S. & Baldwin, S.A.
click here to read abstract

Interleukin 3-mediated cell survival signals include phosphatidylinositol 3-kinase-dependent translocation of the glucose transporter GLUT1 to the cell surface.
(2003)J. Biol Chem. 278, 39337-48.
Bentley, J., Itchayanan, D., Barnes, K., McIntosh, E., Tang, X., Downes, C.P., Holman, G.D., Whetton, A.D., Owen-Lynch, P.J. & Baldwin, S.A.
click here to read abstract

Uridine binding motifs of human concentrative nucleoside transporter 1 and 3 (hCNT1 and HCNT3) produced in Saccharomyces cerevisiae.
(2003) Mol. Pharmacol. 64, 1512-1520.
Zhang, J., Visser, F., Vickers, M.F., Lang, T., Robins, M.J., Nielsen, L., Nowak, I., Baldwin, S.A., Young, J.D. & Cass, C.E.
click here to read abstract

Nucleoside anticancer drugs: the role of nucleoside transporters in resistance to cancer chemotherapy.
(2003) Oncogene 22, 7524-36.
Damaraju, V.L., Damaraju, S., Young, J.D., Baldwin, S.A., Mackey, J., Sawyer, M.B. & Cass, C.E.
click here to read abstract

TOP

2002:

Mutation of residue 33 of human equilibrative nucleoside transporters 1 and 2 (hENT1 and hENT2) alters sensitivity to inhibition of transport by dilazep and dipyridamole
(2002) J. Biol. Chem. 277, 395-401
Visser, F., Vickers, M.F., Ng, A.M.L., Baldwin, S.A., Young, J.D. & Cass, C.E.
click here to read abstract

Immunocytochemical demonstration of the equilibrative nucleoside transporter rENT1 in rat sinoatrial node
(2002) J. Histochem. Cytochem. 50, 305-309
Musa, H., Dobrzynski, H., Berry, Z., Abidi, F., Cass, C.E., Young, J.D., Baldwin, S.A. & Boyett, M.R.
click here to read abstract

Immunohistochemical variation of human equilibrative nucleoside transporter 1 protein in primary breast cancers
(2002) Clin. Cancer Res. 8, 110-116
Mackey, J.R., Jennings, L.L., Clarke, M.L., Santos, C.L., Dabbagh, L., Vsianska, M., Koski, S.L., Coupland, R.W., Baldwin, S.A., Young, J.D. & Cass, C.E.
click here to read abstract

Characterization of the role of the AMP-activated protein kinase in the stimulation of glucose transport in skeletal muscle cells
(2002) Biochem J. 363, 167-174.
Fryer, L.G., Foufelle, F., Barnes, K., Baldwin, S.A., Woods, A.. & Carling D.
click here to read abstract

Activation of GLUT1 by metabolic and osmotic stress: potential involvement of AMP-activated protein kinase (AMPK)
(2002) J. Cell Sci. 115, 2433-2442.
Barnes K., Ingram J.C., Porras O.H., Barros L.F., Hudson E.R., Fryer L.G., Foufelle F., Carling D., Hardie D.G. & Baldwin S.A..
click here to read abstract

An ancient prevertebrate Na(+)-nucleoside cotransporter (hfCNT) from the Pacific hagfish (Eptatretus stouti)
(2002) Am. J. Physiol. Cell Physiol. 283, C155-C168.
Yao S.Y., Ng A.M., Loewen S.K., Cass C.E., Baldwin S.A. & Young J.D.
click here to read abstract

The role of membrane transporters in cellular resistance to anticancer nucleoside drugs.
(2002) In Clinically relevant resistance in cancer chemotherapy (Anderson, B. & Murray, D., eds.) Chapter 2, pp. 27-47, Kluwer Academic Publishers, Boston/Dordrecht/London.
Clarke, M.L., Mackey, J.R., Baldwin, S.A., Young, J.D. & Cass, C.E.

Differential expression of human equilibrative nucleoside transporter 1 (hENT1) protein in the Reed-Sternberg cells of Hodgkin's disease.
(2002) Leukemia & Lymphoma 43, 1435-1440.
Reiman, T., Clarke, M.L., Dabbagh, L., Vsianska, M., Coupland, R.W., Belch, A.R., Baldwin, S.A., Young, J.D., Cass, C.E. & Mackey, J.R.
click here to read abstract

Molecular biology and regulation of nucleoside and nucleobase transporter proteins in eukaryotes and prokaryotes.
(2002) Biochem. Cell Biol. 80, 623-38.
Cabrita, M.A., Baldwin, S.A., Young, J.D.,& Cass, C.E.
click here to read abstract

Comparison of the interaction of uridine, cytidine, and other pyrimidine nucleoside analogues with recombinant human equilibrative nucleoside transporter 2 (hENT2) produced in Saccharomyces cerevisiae.
(2002) Biochem. Cell Biol. 80, 639-44.
Vickers, M.F., Kumar, R., Visser, F., Zhang, J., Charania, J., Raborn, R.T., Baldwin, S.A., Young, J.D. & Cass, C.E.
click here to read abstract