Faculty of Biological Sciences

Dr Thomas Zacharchenko

Research Fellow
School of Biology

Contact:  Miall 8.16, email address for  

Lilja J, Zacharchenko T, Georgiadou M, Jacquemet G, Franceschi ND, Peuhu E, Hamidi H, Pouwels J, Martens V, Nia FH, Beifuss M, Boeckers T, Kreienkamp HJ, Barsukov IL, Ivaska J SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras Nature Cell Biology -, 2017
DOI:10.1038/ncb3487
View abstract

Zacharchenko T, Barsukov I, Rigden DJ, Bennett D, Mayans O Biophysical Analysis of the N-Terminal Domain from the Human Protein Phosphatase 1 Nuclear Targeting Subunit PNUTS Suggests an Extended Transcription Factor TFIIS-Like Fold Protein Journal 35 340-345, 2016
DOI:10.1007/s10930-016-9677-7
View abstract

Zacharchenko T, Qian X, Goult BT, Jethwa D, Almeida TB, Ballestrem C, Critchley DR, Lowy DR, Barsukov IL LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex Structure 24 1130-1141, 2016
DOI:10.1016/j.str.2016.04.016
View abstract

Zacharchenko T, Von Castelmur E, Rigden DJ, Mayans O Structural advances on titin: Towards an atomic understanding of multi-domain functions in myofilament mechanics and scaffolding Biochemical Society Transactions 43 850-855, 2015
DOI:10.1042/BST20150084
View abstract

Goult BT, Zacharchenko T, Bate N, Tsang R, Hey F, Gingras AR, Elliott PR, Roberts GCK, Ballestrem C, Critchley DR, Barsukov IL RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover Journal of Biological Chemistry 288 8238-8249, 2013
DOI:10.1074/jbc.M112.438119