Faculty of Biological Sciences

Dr Kathleen Wright

PhD
Senior Scientific Officer in Cardiovascular Science
School of Biomedical Sciences

Background: Education: (1999-2003) BSc (Hon) Sandwich in Medical Biochemistry, University of Leicester, Leicester, UK (2005-2010) PhD in Biological Sciences based on investigating the nerve sparing effects observed during prostate cancer treatment with Foscan® -mediated photodynamic therapy (PDT). Studied the effect of PDT on MCF-7 cell line and primary mammalian peripheral nerve cells/tissue in 3D tissue engineered co-culture model systems, The Open University, Milton Keynes, UK Relevant Working Experiences: (2001-2002) Industrial Placement in Novel Drug Development for Cystic Fibrosis, Pharmagene Plc, Royston, UK (2002-2003) BSc Project Placement in Novel Drug Development for the Neuropeptide Nociceptin/Orphanin FQ for Nociceptin Receptor (NOP), in Pain Management. Anaesthesia, Critical Care and Pain Management, University of Leicester, Leicester, UK (2003-2005) Cell Culture Scientist in Genetic Reference Material Development, National Institute of Biological Standards & Control (NIBSC), Potters Bar, UK (2010) Postdoctoral Research Fellow (Neuroscience Group Leader) in CNS Regenerative Medicine & Tissue Engineering, Cell Therapy Research Institute (CTI-Lyon), Saint Priest, FR (2011-2013) Postdoctoral Research Associated in Bone Regenerative Medicine & Tissue Engineering, Newcastle University, Newcastle-upon-Tyne, UK. (2013-2015) Senior Postdoctoral Research Fellow (Scientist) Academic Surgery Colorectal Research, Clinical Sciences, Translational Anaesthetics & Surgical Sciences, University of Leeds, Leeds, UK. (2015-present) Senior Scientific Officer in Cardiovascular Sciences, Biomedical Sciences, University of Leeds, UK. Present professional activities: Representative on the FBS Faculty Board Meetings and the Purchasing & Stores Group Meetings. UoL Public Engagement Champion (Necnet) member.

Contact:  Garstang Lab:7.54, Office:7.53, +44(0) 113 34 34244;31869, email address for  

You can read more about Dr Wright's interests here:
https://uk.linkedin.com/in/kathleen-wright-3196a314

https://www.researchgate.net/profile/Kathleen_Wright7/citations?sorting=citationCount&page=1

https://connect.innovateuk.org/web/k.e.wright

http://medhealth.leeds.ac.uk/profile/300/1291/kathleen_e._wright

http://www.leeds.ac.uk/forstaff/info/125151/engagement/1851/engagement_excellence_fellowship

http://www.leedsinspired.co.uk/events/healthy-diet-healthy-heart

http://www.through-the-maze.org.uk/event/chapeltown-arts-festival-2016/

Research Interests

Supporting laboratory research development, training and management in the department of Cardiovascular Sciences



Studentship information

Undergraduate project topics:

  • N/A

Postgraduate studentship areas:

  • MD title: Fluorescence diagnosis using photosensitisers: A useful approach to intraoperative staging in colon cancer?

See also:

Smith AJ, Wright KE, Lewis FC, Ellison GM TYROSINE KINASE INHIBITOR CARDIOTOXICITY AND CARDIAC STEM CELLS, 2016
DOI:10.1136/heartjnl-2016-310696.48

Khaled YS, Wright K, Melcher A, Jayne D Anti-cancer effects of oncolytic viral therapy combined with photodynamic therapy in human pancreatic cancer cell lines, 2015

Almerie MQ, Gossedge G, Wright KE, Jayne DG Photodynamic diagnosis for detection of peritoneal carcinomatosis Journal of Surgical Research 195 175-187, 2015
DOI:10.1016/j.jss.2015.01.009
View abstract

Chen J, Wright KE, Birch MA Nanoscale viscoelastic properties and adhesion of polydimethylsiloxane for tissue engineering Acta Mechanica Sinica/Lixue Xuebao 1-5, 2014
DOI:10.1007/s10409-014-0022-0
View abstract

Forraz N, Wright KE, Jurga M, McGuckin CP Experimental therapies for repair of the central nervous system: stem cells and tissue engineering. J Tissue Eng Regen Med 7 523-536, 2013
DOI:10.1002/term.552
View abstract

Sarnowska A, Jablonska A, Jurga M, Dainiak M, Strojek L, Drela K, Wright K, Tripathi A, Kumar A, Jungvid H, Lukomska B, Forraz N, McGuckin C, Domanska-Janik K Encapsulation of mesenchymal stem cells by bioscaffolds protects cell survival and attenuates neuroinflammatory reaction in injured brain tissue after transplantation. Cell Transplant 22 Suppl 1 S67-S82, 2013
DOI:10.3727/096368913X672172
View abstract

Wright KE, MacRobert AJ, Phillips JB Inhibition of specific cellular antioxidant pathways increases the sensitivity of neurons to meta-tetrahydroxyphenyl chlorin-mediated photodynamic therapy in a 3D co-culture model. Photochem Photobiol 88 1539-1545, 2012
DOI:10.1111/j.1751-1097.2012.01185.x
View abstract

Hawkins M, Boyle J, Wright KE, Elles R, Ramsden SC, O'Grady A, Sweeney M, Barton DE, Burgess T, Moore M, Burns C, Stacey G, Gray E, Metcalfe P, Hawkins JR Preparation and validation of the first WHO international genetic reference panel for Fragile X syndrome. Eur J Hum Genet 19 10-17, 2011
DOI:10.1038/ejhg.2010.135
View abstract

Wright KE, Liniker E, Loizidou M, Moore C, Macrobert AJ, Phillips JB Peripheral neural cell sensitivity to mTHPC-mediated photodynamic therapy in a 3D in vitro model. Br J Cancer 101 658-665, 2009
DOI:10.1038/sj.bjc.6605197
View abstract

Wright KE, McDonald J, Barnes TA, Rowbotham DJ, Guerrini R, Calo' G, Lambert DG Assessment of the activity of a novel nociceptin/orphanin FQ analogue at recombinant human nociceptin/orphanin FQ receptors expressed in Chinese hamster ovary cells. Neurosci Lett 346 145-148, 2003
View abstract

Smith AJ, Wright KE P44 Tyrosine kinase inhibitor cardiotoxicity and cardiac stem cells,