Faculty of Biological Sciences

Dr Roland Remenyi

PhD in Molecular & Medical Pharmacology, UCLA, USA
Research Fellow
School of Molecular and Cellular Biology

Background: At the nexus of Virology and Microscopy.

Contact:  Garstang 7.58, +44(0) 113 34 33068, email address for  

You can read more about Dr Remenyi's interests here:
https://rolandremenyi.wixsite.com/versatilephd

https://www.linkedin.com/in/rolandremenyi/?ppe=1

Research Interests

Developing research tools to visualise viral infection by advanced microscopy

  • Image created with IMARIS software.

Every innovation and advancement starts with great science.

My research focuses on generating tools and platforms to facilitate scientific discovery in virology. I am particularly interested in the role of the nonstructural protein 3 during Chikungunya virus (CHIKV) infection. My goal is to see, visualize, and comprehend the complex interactions between a viral pathogen and the host cell.

 

Current Projects

  • Developing research tools for the study of Chikungunya virus (CHIKV) by advanced microscopy
  • Live cell super-resolution microscopy of CHIKV infection
  • Uncovering interactions between CHIKV nonstructural protein 3 (nsP3) and cellular host proteins
  • Revealing the role of membraneless organelles during the CHIKV life cycle
 

Remenyi R, Roberts GC, Zothner C, Merits A, Harris M SNAP-Tagged Chikungunya Virus Replicons Improve Visualisation of Non-Structural Protein 3 by Fluorescence Microscopy Scientific Reports 7 -, 2017
DOI:10.1038/s41598-017-05820-0
View abstract

Wu NC, Olson CA, Du Y, Le S, Tran K, Remenyi R, Gong D, Al-Mawsawi LQ, Qi H, Wu TT, Sun R Functional Constraint Profiling of a Viral Protein Reveals Discordance of Evolutionary Conservation and Functionality PLoS Genetics 11 -, 2015
DOI:10.1371/journal.pgen.1005310
View abstract

Remenyi R, Qi H, Su SY, Chen Z, Wu NC, Arumugaswami V, Truong S, Chu V, Stokelman T, Lo HH, Anders Olson C, Wu TT, Chen SH, Lin CY, Sun R A comprehensive functional map of the hepatitis C virus genome provides a resource for probing viral proteins mBio 5 -, 2014
DOI:10.1128/mBio.01469-14
View abstract

Qi H, Olson CA, Wu NC, Ke R, Loverdo C, Chu V, Truong S, Remenyi R, Chen Z, Du Y, Su SY, Al-Mawsawi LQ, Wu TT, Chen SH, Lin CY, Zhong W, Lloyd-Smith JO, Sun R A Quantitative High-Resolution Genetic Profile Rapidly Identifies Sequence Determinants of Hepatitis C Viral Fitness and Drug Sensitivity PLoS Pathogens 10 -, 2014
DOI:10.1371/journal.ppat.1004064
View abstract

Kim S, Rusmevichientong A, Dong B, Remenyi R, Silverman RH, Chow SA Fidelity of Target Site Duplication and Sequence Preference during Integration of Xenotropic Murine Leukemia Virus-Related Virus PLoS ONE 5 -, 2010
DOI:10.1371/journal.pone.0010255
View abstract

Barat B, Sirk SJ, McCabe KE, Li J, Lepin EJ, Remenyi R, Ai LK, Olafsen T, Gambhir SS, Weiss S, Wu AM Cys-diabody quantum dot conjugates (ImmunoQdots) for cancer marker detection Bioconjugate Chemistry 20 1474-1481, 2009
DOI:10.1021/bc800421f
View abstract

Arumugaswami V, Remenyi R, Kanagavel V, Sue EY, Ho TN, Liu C, Fontanes V, Dasgupta A, Sun R High-resolution functional profiling of hepatitis C virus genome PLoS Pathogens 4 -, 2008
DOI:10.1371/journal.ppat.1000182
View abstract