Background: At the nexus of Virology and Microscopy.
Contact: Garstang 7.58, +44(0) 113 34 33068,
You can read more about Dr Remenyi's interests here:
Developing research tools to visualise viral infection by advanced microscopy
Every innovation and advancement starts with great science.
My research focuses on generating tools and platforms to facilitate scientific discovery in virology. I am particularly interested in the role of the nonstructural protein 3 during Chikungunya virus (CHIKV) infection. My goal is to see, visualize, and comprehend the complex interactions between a viral pathogen and the host cell.
Wu NC, Olson CA, Du Y, Le S, Tran K, Remenyi R, Gong D, Al-Mawsawi LQ, Qi H, Wu T-T. 2015. Functional constraint profiling of a viral protein reveals discordance of evolutionary conservation and functionality. PLoS Genet doi: 10.1371/journal.pgen.1005310
Remenyi R, Qi H, Su S-Y, Chen Z, Wu NC, Arumugaswami V, Truong S, Chu V, Stokelman T, Lo H-H. 2014. A comprehensive functional map of the hepatitis C virus genome provides a resource for probing viral proteins. MBio doi: 10.1128/mBio.01469-14
Qi H, Olson CA, Wu NC, Ke R, Loverdo C, Chu V, Truong S, Remenyi R, Chen Z, Du Y. 2014. A quantitative high-resolution genetic profile rapidly identifies sequence determinants of hepatitis C viral fitness and drug sensitivity. PLoS Pathog doi.org/10.1371/journal.ppat.1004064
Kim S, Rusmevichientong A, Dong B, Remenyi R, Silverman RH, Chow SA. 2010. Fidelity of target site duplication and sequence preference during integration of xenotropic murine leukemia virus-related virus. PLoS One doi.org/10.1371/journal.pone.0010255
Barat B, Sirk SJ, McCabe KE, Li J, Lepin EJ, Remenyi R, Koh AL, Olafsen T, Gambhir SS, Weiss S. 2009. Cys-diabody quantum dot conjugates (immunoQdots) for cancer marker detection. Bioconjugate chemistry 20:1474-1481. doi.org/10.1021/bc800421f
Arumugaswami V, Remenyi R, Kanagavel V, Sue EY, Ho TN, Liu C, Fontanes V, Dasgupta A, Sun R. 2008. High-resolution functional profiling of hepatitis C virus genome. PLoS Pathog 4:e1000182. doi.org/10.1371/journal.ppat.1000182