Faculty of Biological Sciences

Prof Peter Meyer

DipBiol, PhD 1986, Cologne.
Professor of Plant Genetics
School of Biology

Contact:  Miall 8.24, +44(0) 113 34 33099, email address for  

You can read more about Prof Meyer's interests here:
www.personal.leeds.ac.uk/~genpme/

Research Interests

Plant epigenetics and its role in transgene expression

Epigenetics, chromatin, genome organisation, cytokinins, and transgenic plants.

 

Current Projects

  • Characterisation of chromatin factors involved in transcription, repair and recombination
  • The role of transgene integration regions in transgene expression
  • Removal of selectable marker genes from transgenic plants
  • Plant genes involved in repair and recombination
  • Cytokinin-mediated resistance against biotic stress
  • Cytokinin-mediated delay of senescence
  • Microarray-based analysis of cell-cycle genes and plastid genes
  • Activation tagging of plant genes
 

Faculty Research and Innovation



Studentship information

Postgraduate studentship areas:

  • Epigenetics and gene silencing in plants

See also:

Modules managed

BLGY3232 - Epigenetics
BLGY3291 - Comparative Genomics

Modules taught

BIOL5251M - Plant Biotechnology
BLGY1303 - Tutorials for Biology and Genetics
BLGY2100 - Enhanced Study Skills for Biologists
BLGY3021 - Research Project
BLGY3110 - Applied Genetics
BLGY3232 - Epigenetics
BLGY3291 - Comparative Genomics
BLGY3340 - Biology Research Projects
BLGY5380M - Extended Research Project
FOBS1135/BLGY1115 - The Basis of Life/Introduction to Cell Biology: from Molecules to Cells and Tissues

Committees

Member of Graduate School Committee (Progression Tutor (SB))

Centre membership: The Centre for Plant Sciences

Group Leader Prof Peter Meyer  (Professor of Plant Genetics)

Plant epigenetics and its role in transgene expression 

Postgraduates

Samuel Brocklehurst (Primary supervisor) 100% FTE
Elizabeth Hollwey (Primary supervisor) 100% FTE
Najihah Binti Mohamed (Primary supervisor) 90% FTE
Rachel O'Neill (Co-supervisor) 10% FTE

Meyer P DNA methylation systems and targets in plants FEBS letters 585 2008-2015, 2010
DOI:10.1016/j.febslet.2010.08.017
View abstract

Vassileva V, Hollwey E, Todorov D, Meyer P Leaf epidermal profiling as a phenotyping tool for DNA methylation mutants Genetics and Plant Physiology 6 3-13, 2016
View abstract

Watson MR, Lin YF, Hollwey E, Dodds RE, Meyer P, McDowall KJ An improved binary vector and escherichia coli strain for agrobacterium tumefaciens-mediated plant transformation G3: Genes, Genomes, Genetics 6 2195-2201, 2016
DOI:10.1534/g3.116.029405
View abstract

Hollwey E, Watson M, Meyer P Expression of the C-Terminal Domain of Mammalian TET3 DNA Dioxygenase in Arabidopsis thaliana Induces Heritable Methylation Changes at rDNA Loci Advances in Bioscience and Biotechnology 7 243-250, 2016
DOI:10.4236/abb.2016.75023
View abstract

Meyer P Epigenetic variation and environmental change. J Exp Bot 66 3541-3548, 2015
DOI:10.1093/jxb/eru502
View abstract

Watson M, Hawkes E, Meyer P Transmission of epi-alleles with MET1-dependent dense methylation in Arabidopsis thaliana. PLoS One 9 e105338-, 2014
DOI:10.1371/journal.pone.0105338
View abstract

Gentry M, Meyer P An 11bp region with stem formation potential is essential for de novo DNA methylation of the RPS element PLoS One 8 -, 2013
DOI:10.1371/journal.pone.0063652
View abstract

Meyer P Transgenes and their contributions to epigenetic research The International Journal of Developmental Biology 57 509-515, 2013
DOI:10.1387/ijdb.120254pm
View abstract

Zubko E, Gentry M, Kunova A, Meyer P De novo DNA methylation activity of METHYLTRANSFERASE 1 (MET1) partially restores body methylation in Arabidopsis thaliana Plant Journal 71 1029-1037, 2012
DOI:10.1111/j.1365-313X.2012.05051.x
View abstract

Kunova A, Zubko E, Meyer P A pair of partially overlapping Arabidopsis genes with antagonistic circadian expression. Int J Plant Genomics 2012 349527-, 2012
DOI:10.1155/2012/349527
View abstract

Zubko E, Kunova A, Meyer P Sense and Antisense Transcripts of Convergent Gene Pairs in Arabidopsis thaliana Can Share a Common Polyadenylation Region PLOS ONE 6 -, 2011
DOI:10.1371/journal.pone.0016769

Tedder P, Zubko E, Westhead DR, Meyer P Small RNA analysis in Petunia hybrida identifies unusual tissue-specific expression patterns of conserved miRNAs and of a 24mer RNA RNA 15 1012-1020, 2009
DOI:10.1261/rna.1517209

Singh A, Zubko E, Meyer P Cooperative activity of DNA methyltransferases for maintenance of symmetrical and non-symmetrical cytosine methylation in Arabidopsis thaliana PLANT J 56 814-823, 2008
DOI:10.1111/j.1365-313X.2008.03640.x

Adamo A, Pinney JW, Kunova A, Westhead DR, Meyer P Heat Stress Enhances the Accumulation of Polyadenylated Mitochondrial Transcripts in Arabidopsis thaliana PLOS ONE 3 -, 2008
DOI:10.1371/journal.pone.0002889

Zubko E, Meyer P A natural antisense transcript of the Petunia hybrida Sho gene suggests a role for an antisense mechanism in cytokinin regulation PLANT J 52 1131-1139, 2007
DOI:10.1111/j.1365-313X.2007.03309.x

Meyer P Annual Plant Reviews, 2007
DOI:10.1002/9780470988626
View abstract

Meyer P Gene silencing in Plants In Encyclopedia of Life Sciences , 2006
DOI:10.1038/npg.els0020064

Zubko E, Machackova I, Malbeck J, Meyer P Modification of cytokinin levels in potato via expression of the Petunia hybrida Sho gene TRANSGENIC RES 14 615-618, 2005
DOI:10.1007/s11248-005-2029-6

Jen C-H, Michalopoulos I, Westhead DR, Meyer P Natural antisense transcripts with coding capacity in Arabidopsis may have a regulatory role that is not linked to double-stranded RNA degradation. Genome Biol 6 R51-, 2005
DOI:10.1186/gb-2005-6-6-r51
View abstract

Depicker A, Sanders M, Meyer P Transgene silencing In Annual Plant Reviews: Plant Epigenetics , 2005

Meyer P Plant Epigenetics, 2005

Meyer P Plant Epigenetics Preface PLANT EPIGENETICS 19 XVI-XVI, 2005

Zubko MK, Zubko EI, van Zuilen K, Meyer P, Day A Stable transformation of petunia plastids TRANSGENIC RES 13 523-530, 2004

Stevens R, Grelon M, Vezon D, Oh JS, Meyer P, Perennes C, Domenichini S, Bergounioux C A CDC45 homolog in Arabidopsis is essential for meiosis, as shown by RNA interference-induced gene silencing PLANT CELL 16 99-113, 2004
DOI:10.1105/tpc.016865

Meyer P Introduction: epigenetic strategies in animals and plants. Semin Cell Dev Biol 14 51-52, 2003

Meyer P Epigenetic strategies in animals and plants Seminars in Cell and Developmental Biology 14 51-52, 2003
DOI:10.1016/S1084-9521(02)00136-2

Zubko E, Adams CJ, Machaekova I, Malbeck J, Scollan C, Meyer P Activation tagging identifies a gene from Petunia hybrida responsible for the production of active cytokinins in plants PLANT J 29 797-808, 2002

Müller A, Marins M, Kamisugi Y, Meyer P Analysis of hypermethylation in the RPS element suggests a signal function for short inverted repeats in de novo methylation. Plant Mol Biol 48 383-399, 2002
View abstract

Scutt CP, Zubko EI, Meyer P Techniques for the removal of marker genes from transgenic plants Biochimie 84 1119-1126, 2002
DOI:10.1016/S0300-9084(02)00021-4

Meyer P Chromatin remodelling Current Opinion in Plant Biology 4 457-462, 2001
DOI:10.1016/S1369-5266(00)00200-4

Charrier B, Scollan C, Ross S, Zubko E, Meyer P Co-silencing of homologous transgenes in tobacco MOL BREEDING 6 407-419, 2000

Meyer P Transcriptional transgene silencing and chromatin components PLANT MOL BIOL 43 221-234, 2000

Zubko E, Scutt C, Meyer P Intrachromosomal recombination between attP regions as a tool to remove selectable marker genes from tobacco transgenes NAT BIOTECHNOL 18 442-445, 2000

Kooter JM, Matzke MA, Meyer P Listening to the silent genes: transgene silencing, gene regulation and pathogen control TRENDS IN PLANT SCIENCE 4 340-347, 1999
DOI:10.1016/S1360-1385(99)01467-3

Muller AE, Kamisugi Y, Gruneberg R, Niedenhof I, Horold RJ, Meyer P Palindromic sequences and A plus T-rich DNA elements promote illegitimate recombination in Nicotiana tabacum J MOL BIOL 291 29-46, 1999

Ingram R, Charrier B, Scollan C, Meyer P Transgenic tobacco plants expressing the Drosophila Polycomb (Pc) chromodomain show developmental alterations: Possible role of Pc chromodomain proteins in chromatin-mediated gene regulation in plants PLANT CELL 11 1047-1060, 1999

Meyer P The role of chromatin remodelling in transgene silencing and plant development In Vitro Cellular&Developmental Biology - Plant 35 29-36, 1999

van Blokland R, Ross S, Corrado G, Scollan C, Meyer P Developmental abnormalities associated with deoxyadenosine methylation in transgenic tobacco. The Plant Journal 15 543-551, 1998
View abstract

Meyer P Stabilities and instabilities of transgene expression In Transgenic Plant Research , 1998

van Blokland R, ten Lohuis M, Meyer P Condensation of chromatin in transcriptional regions of an inactivated plant transgene: evidence for an active role of transcription in gene silencing. Mol Gen Genet 257 1-13, 1997
View abstract

Meyer P Inactivation of gene expression in transgenic plants In Transgenic organisms - biological and social implications , 1996

Meyer P DNA methylation of flower colour transgenes in Petunia hydrida In Epigenic mechanisms of gene regulation , 1996

Meyer P, ten Lohuis M, van Blokland R, Heidmann I, Neiderhof I The role of DNA methylation in transgene silencing in plants In Mechanisms and applications of gene silencing , 1996

Meyer P Repeat-induced gene silencing: Common mechanisms in plants and fungi. Biological Chemistry Hoppe-Seyler 377 87-95, 1996

Meyer P Homology-dependent gene silencing in plants. Annual Review of Plant Physiology and Plant Molecular Biology 47 23-48, 1996

MEYER P UNDERSTANDING AND CONTROLLING TRANSGENE EXPRESSION TRENDS BIOTECHNOL 13 332-337, 1995

Galliano H, Müller AE, Lucht JM, Meyer P The transformation booster sequence from Petunia hybrida is a retrotransposon derivative that binds to the nuclear scaffold. Mol Gen Genet 247 614-622, 1995
View abstract

ten Lohuis M, Galliano H, Heidmann I, Meyer P Treatment with propionic and butyric acid enhances expression variegation and promoter methylation in plant transgenes. Biol Chem Hoppe Seyler 376 311-320, 1995
View abstract

MEYER P DNA METHYLATION AND TRANSGENE SILENCING IN PETUNIA-HYBRIDA CURR TOP MICROBIOL 197 15-28, 1995

Meyer P A repetitive DNA-fragment carrying a hot spot for de novo DNA methylation enhances expression variegation in tobacco and petunia The Plant Journal 8 919-932., 1995

Meyer P, Heidmann I Epigenetic variants of a transgenic petunia line show hypermethylation in transgene DNA: an indication for specific recognition of foreign DNA in transgenic plants. Mol Gen Genet 243 390-399, 1994
View abstract

Meyer P Evidence for cytosine methylation of non symmetrical sequences in plants. The EMBO Journal 13 2084-2088., 1994

ten Lohuis MR, Meyer A, Meyer P An improved method for the isolation of high molecular weight>300 kb plant DNA in liquid phase. Biotechniques 14 890-892, 1993

ENGELS P, MEYER P INACTIVATION OF THE TRANSCRIPTIONAL-DEPENDENT INHIBITION OF PLASMID REPLICATION - A SELECTION METHOD FOR CLONING LARGE DNA FRAGMENTS BIOTECHNIQUES 14 324-325, 1993

Meyer P Difference in DNA-methylation are associated with a paramutation phenomenon in transgenic petunia The Plant Journal 4 89-100., 1993

PROLS F, MEYER P THE METHYLATION PATTERNS OF CHROMOSOMAL INTEGRATION REGIONS INFLUENCE GENE ACTIVITY OF TRANSFERRED DNA IN PETUNIA-HYBRIDA PLANT J 2 465-475, 1992

MEYER P, LINN F, HEIDMANN I, MEYER H, NIEDENHOF I, SAEDLER H ENDOGENOUS AND ENVIRONMENTAL-FACTORS INFLUENCE 35S PROMOTER METHYLATION OF A MAIZE A1 GENE CONSTRUCT IN TRANSGENIC PETUNIA AND ITS COLOR PHENOTYPE MOL GEN GENET 231 345-352, 1992

Meyer P, Heidmann I, Niedenhof I The use of African cassava mosaic virus as a vector system for plants. Gene 110 213-217, 1992
View abstract

ENGELS P, MEYER P COMPARISON OF HOMOLOGOUS RECOMBINATION FREQUENCIES IN SOMATIC-CELLS OF PETUNIA AND TOBACCO SUGGEST 2 DISTINCT RECOMBINATION PATHWAYS PLANT J 2 59-67, 1992

Linn F, Heidmann I, Saedler H, Meyer P Epigenetic changes in the expression of the maize A1 gene in Petunia hybrida: role of numbers of integrated gene copies and state of methylation. Mol Gen Genet 222 329-336, 1990
View abstract

KARTZKE S, SAEDLER H, MEYER P MOLECULAR ANALYSIS OF TRANSGENIC PLANTS DERIVED FROM TRANSFORMATIONS OF PROTOPLASTS AT VARIOUS STAGES OF THE CELL-CYCLE PLANT SCI 67 63-72, 1990

MEYER P, NIEDENHOF I, HEIDMANN I, SAEDLER H EXTRACHROMOSOMAL FORMS OF CLV DNA1 IN TRANSGENIC PLANTS ARE INHERITED BY SYMPTOM-FREE PROGENY PLANT SCI 65 207-216, 1989

Meyer P, Kartzke S, Niedenhof I, Heidmann I, Bussmann K, Saedler H A genomic DNA segment from Petunia hybrida leads to increased transformation frequencies and simple integration patterns. Proc Natl Acad Sci U S A 85 8568-8572, 1988
View abstract

Meyer P, Heidmann I, Forkmann G, Saedler H A new petunia flower colour generated by transformation of a mutant with a maize gene. Nature 330 677-678, 1987
DOI:10.1038/330677a0
View abstract

MEYER P, WALGENBACH E, BUSSMANN K, HOMBRECHER G, SAEDLER H SYNCHRONIZED TOBACCO PROTOPLASTS ARE EFFICIENTLY TRANSFORMED BY DNA MOL GEN GENET 201 513-518, 1985