Faculty of Biological Sciences

Dr Dan Donnelly

BSc, Leicester; PhD 1992, London.
Senior Lecturer
School of Biomedical Sciences

Contact:  Garstang 6.41d | +44(0) 113 34 37761 | email address for  

Research Interests

G Protein-Coupled Receptor - structure and function.

 

GLP-1, PTH and CGRP receptors

 

Current Projects

The laboratory studies the structure & function of G protein-coupled receptors - one of the most diverse and ubiquitous families of integral membrane proteins. GPCRs play a pivotal role in many cellular signalling pathways and are prime targets for the development of therapeutic agents designed to either block or activate the receptors. The aim of this laboratory is to elucidate the mechanism by which these receptors bind their ligands and transduce the signal across the plasma membrane. The research in my lab concentrates primarily on the glucagon-like peptide-1 (GLP-1) receptor (funded by BBSRC & AstraZeneca; previous funding has come from Novo Nordisk, The Royal Society, BBSRC and Diabetes UK) and the parathyroid hormone and CRLR receptors (funding from GSK & BBSRC).

 

Faculty Research and Innovation



Studentship information

Undergraduate project topics:

  • G Protein-Coupled Receptor - structure and function.

Postgraduate studentship areas:

  • The Structure and Function of the 7TM Receptor for Glucagon-like Peptide-1 (GLP-1)

See also:

Admin roles

FBS FTSEC
FBS UGTSEC
Library Representative
UG Programme Leader: Pharmacology

Modules managed

BMSC2224 - Principles of Drug Discovery
BMSC3143 - Advanced Topics in Pharmacology I
BMSC3233 - Advanced Topics in Pharmacology II

Modules taught

BIOC3221/22/23/BIOL3210 - ATU 23 - Membrane proteins
BMSC1103 - Basic Laboratory and Scientific Skills
BMSC1110/SPSC1220 - Foundation modules
BMSC1212 - Introduction to Pharmacology
BMSC1213 - Basic Laboratory and Scientific Skills 2
BMSC2119 - Experimental Skills
BMSC2119/3302 - Experimental Skills/Medical Pharmacology
BMSC2224 - Principles of Drug Discovery
BMSC2230 - Topics in Pharmacology
BMSC3143 - Advanced Topics in Pharmacology I
BMSC3143/44/45/46 - ATUs - BMS specific
BMSC3233 - Advanced Topics in Pharmacology II
BMSC3301 - Research Proj: Biomed Sciences

Committees

Member of Undergraduate School Taught Student Education Committee

Group Leader Dr Dan Donnelly  (Senior Lecturer)

G Protein-Coupled Receptor - structure and function.