Faculty of Biological Sciences

Dr Dan Donnelly

BSc, Leicester; PhD 1992, London.
Senior Lecturer
School of Biomedical Sciences

Contact:  Garstang 6.41d, +44(0) 113 34 37761, email address for  

Research Interests

G Protein-Coupled Receptor - structure and function.


GLP-1, PTH and CGRP receptors


Current Projects

The laboratory studies the structure & function of G protein-coupled receptors (GPCRs) - one of the most diverse and ubiquitous families of integral membrane proteins, which also represent a significant proportion of known drug targets. Using molecular biological & pharmacological approaches, combined with molecular modelling, the aim of this research is to elucidate the mechanism by which these receptors bind their ligands and transduce the signal across the plasma membrane. The research concentrates primarily on the glucagon-like peptide-1 (GLP-1) receptor and the parathyroid hormone receptors (PTH1 and PTH2).


Faculty Research and Innovation

Studentship information

Undergraduate project topics:

  • G Protein-Coupled Receptor - structure and function.

Postgraduate studentship areas:

  • The Structure and Function of the 7TM Receptor for Glucagon-like Peptide-1 (GLP-1)

See also:

Modules managed

BMSC2224 - Principles of Drug Discovery
BMSC3143 - Advanced Topics in Pharmacology I
BMSC3233 - Advanced Topics in Pharmacology II

Modules taught

BMSC1110/SPSC1220 - Foundation modules
BMSC1212 - Introduction to Pharmacology
BMSC1213 - Basic Laboratory and Scientific Skills 2
BMSC2119 - Experimental Skills
BMSC2119/3302 - Experimental Skills/Medical Pharmacology
BMSC2224 - Principles of Drug Discovery
BMSC2226 - Experimental Skills in Pharmacology
BMSC2230 - Topics in Pharmacology
BMSC3143/44/45/46 - Advanced topics for BMS students I
BMSC3301 - Research Project in Biomedical Sciences
BMSC3302 - Medical Pharmacology


Member of Faculty Taught Student Education Committee (Co-opted member)
Member of Undergraduate School Taught Student Education Committee (Programme Manager: Pharmacology)

Group Leader Dr Dan Donnelly  (Senior Lecturer)

G Protein-Coupled Receptor - structure and function. 


Carla Gómez Santiago (Primary supervisor) 50% FTE
James Henderson (Co-supervisor) 50% FTE