Faculty of Biological Sciences

Dr Selena Burgess

Research Fellow
School of Molecular and Cellular Biology

Contact:  Astbury 6.107, +44(0) 113 34 None, email address for  

McIntyre PJ, Collins PM, Vrzal L, Birchall K, Arnold LH, Mpamhanga C, Coombs PJ, Burgess SG, Richards MW, Winter A, Veverka V, Delft FV, Merritt A, Bayliss R Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches. ACS chemical biology -, 2017
DOI:10.1021/acschembio.7b00537
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Bayliss R, Burgess SG, McIntyre PJ Switching Aurora-A kinase on and off at an allosteric site FEBS Journal 284 2947-2954, 2017
DOI:10.1111/febs.14069
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Bayliss R, Burgess SG, Leen E, Richards MW A moving target: Structure and disorder in pursuit of Myc inhibitors Biochemical Society Transactions 45 709-717, 2017
DOI:10.1042/BST20160328
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Burgess SG, Grazia Concilio M, Bayliss R, Fielding AJ Detection of Ligand-induced Conformational Changes in the Activation Loop of Aurora-A Kinase by PELDOR Spectroscopy ChemistryOpen 5 531-534, 2016
DOI:10.1002/open.201600101
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Richards MW, Burgess SG, Poon E, Carstensen A, Eilers M, Chesler L, Bayliss R Structural basis of N-Myc binding by Aurora-A and its destabilization by kinase inhibitors Proceedings of the National Academy of Sciences of the United States of America 113 13726-13731, 2016
DOI:10.1073/pnas.1610626113
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Burgess SG, Oleksy A, Cavazza T, Richards MW, Vernos I, Matthews D, Bayliss R Allosteric inhibition of Aurora-A kinase by a synthetic vNAR domain Open Biology 6 -, 2016
DOI:10.1098/rsob.160089
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Concilio MG, Fielding AJ, Bayliss R, Burgess SG Density functional theory studies of MTSL nitroxide side chain conformations attached to an activation loop Theoretical Chemistry Accounts 135 -, 2016
DOI:10.1007/s00214-016-1859-z
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Haq T, Richards MW, Burgess SG, Gallego P, Yeoh S, O'Regan L, Reverter D, Roig J, Fry AM, Bayliss R Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization Nature Communications 6 -, 2015
DOI:10.1038/ncomms9771
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Burgess SG, Bayliss R, Pfuhl M Solution NMR assignment of the cryptic sixth TOG domain of mini spindles Biomolecular NMR Assignments 9 411-413, 2015
DOI:10.1007/s12104-015-9620-4
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Gutiérrez-Caballero C, Burgess SG, Bayliss R, Royle SJ TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation Biology Open 4 170-179, 2015
DOI:10.1242/bio.201410843
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Burgess SG, Peset I, Joseph N, Cavazza T, Vernos I, Pfuhl M, Gergely F, Bayliss R Aurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle Assembly PLoS Genetics 11 -, 2015
DOI:10.1371/journal.pgen.1005345
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Burgess SG, Bayliss R The structure of C290A: C393A Aurora A provides structural insights into kinase regulation Acta Crystallographica Section F:Structural Biology Communications 71 315-319, 2015
DOI:10.1107/S2053230X15002290
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Hood FE, Williams SJ, Burgess SG, Richards MW, Roth D, Straube A, Pfuhl M, Bayliss R, Royle SJ Coordination of adjacent domains mediates TACC3-ch-TOG-clathrin assembly and mitotic spindle binding Journal of Cell Biology 202 463-478, 2013
DOI:10.1083/jcb.201211127
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Burgess SG, Messiha HL, Katona G, Rigby SEJ, Leys D, Scrutton NS Probing the dynamic interface between trimethylamine dehydrogenase (TMADH) and electron transferring flavoprotein (ETF) in the TMADH-2ETF complex: Role of the Arg-α237 (ETF) and Tyr-442 (TMADH) residue pair Biochemistry 47 5168-5181, 2008
DOI:10.1021/bi800127d
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