Faculty of Biological Sciences

Dr Joseph Ainscough

Research Fellow
School of Molecular and Cellular Biology

Contact:  Garstang 8.53, +44(0) 113 34 32990, email address for  

Ainscough JS, MacLeod T, McGonagle D, Brakefield R, Baron JM, Alase A, Wittmann M, Stacey M Cathepsin S is the major activator of the psoriasisassociated proinflammatory cytokine IL-36γ Proceedings of the National Academy of Sciences of the United States of America 114 E2748-E2757, 2017
DOI:10.1073/pnas.1620954114
View abstract

Wittmann M, Macleod T, Ainscough JS, Alase A, McGonagle D, Doble R, Latzko A, Stacey M Activation of IL-36 molecules and their role in psoriatic disease., 2016

Ainscough JS, Macleod T, Alase A, Latzko A, Whittmann M, Stacey M Cathepsin S is up-regulated in psoriatic inflammation and activates the pro-inflammatory cytokine IL-36 gamma, 2016

Ainscough JS, Gerberick GF, Kimber I, Dearman RJ Interleukin-1β processing is dependent on a calcium-mediated interaction with calmodulin Journal of Biological Chemistry 290 31151-31161, 2015
DOI:10.1074/jbc.M115.680694
View abstract

Englezou PC, Rothwell SW, Ainscough JS, Brough D, Landsiedel R, Verkhratsky A, Kimber I, Dearman RJ P2X<inf>7</inf>R activation drives distinct IL-1 responses in dendritic cells compared to macrophages Cytokine 74 293-304, 2015
DOI:10.1016/j.cyto.2015.05.013
View abstract