Faculty of Biological Sciences

Publications

Aspden JL, Eyre-Walker YC, Phillips RJ, Amin U, Mumtaz MAS, Brocard M, Couso J-P Extensive translation of small Open Reading Frames revealed by Poly-Ribo-Seq Elife 3 -, 2014
DOI:10.7554/eLife.03528
View abstract

Rogulja-Ortmann A, Picao-Osorio J, Villava C, Patraquim P, Lafuente E, Aspden J, Thomsen S, Technau GM, Alonso CR The RNA-binding protein ELAV regulates Hox RNA processing, expression and function within the Drosophila nervous system. Development 141 2046-2056, 2014
DOI:10.1242/dev.101519
View abstract

Taliaferro JM, Aspden JL, Bradley T, Marwha D, Blanchette M, Rio DC Two new and distinct roles for Drosophila Argonaute-2 in the nucleus: alternative pre-mRNA splicing and transcriptional repression. Genes Dev 27 378-389, 2013
DOI:10.1101/gad.210708.112
View abstract

Taliaferro JM, Marwha D, Aspden JL, Mavrici D, Cheng NE, Kohlstaedt LA, Rio DC The Drosophila splicing factor PSI is phosphorylated by casein kinase II and tousled-like kinase. PLoS One 8 e56401-, 2013
DOI:10.1371/journal.pone.0056401
View abstract

Brooks AN, Aspden JL, Podgornaia AI, Rio DC, Brenner SE Identification and experimental validation of splicing regulatory elements in Drosophila melanogaster reveals functionally conserved splicing enhancers in metazoans. RNA 17 1884-1894, 2011
DOI:10.1261/rna.2696311
View abstract

Hellsten U, Aspden JL, Rio DC, Rokhsar DS A segmental genomic duplication generates a functional intron. Nat Commun 2 454-, 2011
DOI:10.1038/ncomms1461
View abstract

Song EJ, Werner SL, Neubauer J, Stegmeier F, Aspden J, Rio D, Harper JW, Elledge SJ, Kirschner MW, Rape M The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome. Genes Dev 24 1434-1447, 2010
DOI:10.1101/gad.1925010
View abstract

Aspden JL, Jackson RJ Differential effects of nucleotide analogs on scanning-dependent initiation and elongation of mammalian mRNA translation in vitro. RNA 16 1130-1137, 2010
DOI:10.1261/rna.1978610
View abstract