Faculty of Biological Sciences

Aiming to enhance understanding of the functions of the nervous system to provide avenues for new therapies.

Our neuroscience research targets understanding the function of proteins such as ion channels, gap junctions, neurotransmitter receptors and transporters on the characteristics of neurones and factors affecting the functions of these proteins. We aim to understand the nervous system from gene regulation to whole organism function, to bring forward therapies to nervous disorders such as pain, hypertension, epilepsy, neurodegeneration, spinal cord injury and behavioural dysfunction.

To achieve our aims we work alongside colleagues in cross faculty initiatives (NeuR@L) as well as with colleagues in Integrative Membrane Biology, Structural Molecular Biology, Multidisciplinary Cardiovascular Research Centre and the Leeds Psychosis Research Group.

Key researchers in this area

  • Understanding how proteins such as ion channels, neurotransmitter receptors, transporters and gap junctions work to influence neuronal function and behaviour
  • Dr Steven Clapcote, Lecturer in Pharmacology
    Genetic basis of neurological and psychiatric disorders
    Research interests
  • Dr Susan Deuchars, Reader in Neuroscience
    Ion channels, neurotransmitter receptors, transporters and gap junctions influence neuronal and circuit function in the brainstream and spinal cord
    Research interests
  • Prof James Deuchars, Professor of Systems Neuroscience
    How expression of ion channels, neurotransmitter receptors, transporters and gap junctions influence neuronal and circuit function in the brainstem and spinal cord
    Research interests
  • Dr Beatrice Maria Filippi, UAF in Neuroscience
    How Insulin resistance in the brain affects the metabolic behaviour and favours neurodegeneration.
    Research interests
  • Prof Nikita Gamper, Professor of Neuroscience
    Ion channels in sensory neurones and modulation in pain
    Research interests
  • Prof Adrian Goldman, Chair in Membrane Biology
    Research interests
  • Prof Ian Hope, Professor of Invertebrate Developmental Genetics
    Animal Development, Gene Expression and Locomotion In The Nematode, Caenorhabditis elegans
    Research interests
  • Prof Elwyn Isaac, Professor of Comparative Biochemistry
    Comparative biochemistry and functional genomics of neuropeptides and peptidases
    Research interests
  • Dr Lin-Hua Jiang, Lecturer
    Molecular mechanisms of ion channels in health and disease
    Research interests
  • Dr Jamie Johnston, UAF in Neuroscience
    Computations in neural circuits
    Research interests
  • Prof Anne King, Chair of Translational Neuroscience
    How ion channels, gap junction and transporters influence pain processing in the dorsal horn
    Research interests
  • Dr Jessica Kwok, University Academic Fellow in Medical Engineering in the Spinal Cord
    Enhancement of plasticity for recovery in spinal cord injury and neural degenerative diseases
    Research interests
  • Dr Jonathan Lippiat, Lecturer
    Molecular properties and pharmacology of ion channels and transporters
    Research interests
  • Dr Glenn McConkey, Senior Lecturer
    Manipulation of neurotransmitters and behaviour by parasitic infections
    Research interests
  • Dr Hugh Pearson, Senior Lecturer
    Voltage gated ion channels and Alzheimer's disease
    Research interests
  • Dr Ian Wood, Senior Lecturer in Neuroscience
    Regulation of expression of ion channel genes in normal physiology and in neuronal disorders such as epilepsy and chronic pain
    Research interests
  • Function and repair of neuronal networks in the spinal cord and spinal sensory inputs
  • Dr Samit Chakrabarty, Lecturer in Neuroscience
    Spinal motor neurophysiology
    Research interests
  • Prof James Deuchars, Professor of Systems Neuroscience
    Spinal cord circuitry controlling autonomic nrevous output, spinal neurogenesis
    Research interests
  • Dr Susan Deuchars, Reader in Neuroscience
    Spinal cord circuitry controlling autonomic nervous output, spinal neurogenesis
    Research interests
  • Prof Nikita Gamper, Professor of Neuroscience
    Sensory neurones invloved in pain pathways
    Research interests
  • Dr Ronaldo Ichiyama, Associate Professor in Motor Control
    Activity dependant plasticity in the spinal cord; spinal cord injury - neural regeneration and functional recovery
    Research interests
  • Prof Anne King, Chair of Translational Neuroscience
    Dorsal horn circuitry in pain pathways
    Research interests
  • Dr Jessica Kwok, University Academic Fellow in Medical Engineering in the Spinal Cord
    Enhancement of plasticity for recovery in spinal cord injury and neural degenerative diseases
    Research interests
  • Neurodegeneration
  • Dr Steven Clapcote, Lecturer in Pharmacology
    Genetic basis of neurological and psychiatric disorders
    Research interests
  • Dr Beatrice Maria Filippi, UAF in Neuroscience
    How Insulin resistance in the brain affects the metabolic behaviour and favours neurodegeneration.
    Research interests
  • Dr Ronaldo Ichiyama, Associate Professor in Motor Control
    Neurodegenerative changes following spinal cord injury
    Research interests
  • Dr Lin-Hua Jiang, Lecturer
    Molecular mechanisms of ion channels in health and disease
    Research interests
  • Dr Jessica Kwok, University Academic Fellow in Medical Engineering in the Spinal Cord
    Enhancement of plasticity for recovery in spinal cord injury and neural degenerative diseases
    Research interests
  • Dr Glenn McConkey, Senior Lecturer
    Can parasitic infections contribute to neurodegenerative disorders?
    Research interests
  • Dr Hugh Pearson, Senior Lecturer
    Voltage gated ion channels in Alzheimer's disease; physiological functions of beta amyloid
    Research interests
  • Prof Sheena Radford, FMedSci, FRS, Astbury Professor of Biophysics
    Amyloidogenic diseases, mechanisms of protein folding and misfolding in vitro and in vivo
    Research interests
  • Prof Anthony Turner, Emeritus Professor of Biochemistry
    Termination of neuronal signalling by the neprilysin family, proteolytic events involved in the production and removal of the b-amyloid peptide
    Research interests
  • Dr Patricija van Oosten-Hawle, Lecturer in Cell Biology
    Proteostasis mechanisms in health and neurodegenerative diseases
    Research interests
  • Dr Ian Wood, Senior Lecturer in Neuroscience
    The role of HDACs in neurodegenerative conditions
    Research interests