Faculty of Biological Sciences

Fundamental mechanisms and translational research in animal development, husbandry and disease

We use a variety of model organisms to investigate fundamental processes in animal development and disease. We are interested in the molecular mechanisms and genetics involved in human disease states including parasitic infections, congenital disorders and cancer. Our work has diverse applications ranging from the improvement of animal performance in farming through to the design of therapeutic drugs for medical purposes.

Key researchers in this area

  • Heredity, Development and Disease
  • Dr Julie Aspden, University Academic Fellowship in Pervasive Transcription
    RNA Biology: mRNA translation, long non-coding RNAs and RNA-binding proteins in Drosophila
    Research interests
  • Dr Amanda Bretman, Lecturer in Animal Biology
    Evolutionary ecologist specialising in sexual selection and social behaviours
    Research interests
  • Dr Edwin Chen, University Academic Fellowship in Molecular Mechanisms of Cancer Biology
    Molecular basis and clonal evolution of myeloid malignancies
    Research interests
  • Dr Ron Chen, University Academic Fellowship in Pervasive Transcription
    Epigenetic control in transcription regulation using functional genetics and genomics
    Research interests
  • Dr Elizabeth Duncan, Lecturer in Zoology
    Evolution of eusociality, phenotypic plasticity, invertebrate developmental biology, evolution of developmental pathways, genome architecture and evolution
    Research interests
  • Dr Simon Goodman, Lecturer
    Population and conservation genetics, molecular ecology, disease ecology
    Research interests
  • Dr Henry Greathead, Lecturer
    Ruminants: nutrition; growth; metabolism; Plant extracts/secondary metabolites
    Research interests
  • Prof Ian Hope, Professor of Invertebrate Developmental Genetics
    Neuronal control of locomotion in model organisms
    Research interests
  • Prof Elwyn Isaac, Professor of Comparative Biochemistry
    Comparative biochemistry and functional genomics of neuropeptides and peptidases
    Research interests
  • Dr Glenn McConkey, Senior Lecturer
    Can parasitic infections contribute to neurodegenerative disorders?
    Research interests
  • Prof Helen Miller, Professor of Animal Bioscience
    Nutrition of pigs and poultry with particular emphasis on health, feed intake and nutrient partitioning for production.
    Research interests
  • Dr Mary O'Connell, University Academic Fellow in Biology
    Study of the patterns and processes of molecular evolution using large scale sequencing data
    Research interests
  • Dr Andrew Peel, Lecturer in Animal Biology
    Research interests
  • Dr Rupert Quinnell, Senior Lecturer
    Population biology and control of parasitic diseases
    Research interests
  • Dr Patricija van Oosten-Hawle, Lecturer in Cell Biology
    Proteostasis mechanisms in health and neurodegenerative diseases
    Research interests
  • Dr Stephanie Wright, Senior Lecturer
    Cancer biology, transcription factors, protein degradation, protein-protein interactions, structural biology, X-ray crystallography
    Research interests