Faculty of Biological Sciences

Feline friends?

6th September 2012

A report showing that 350,000 people in the UK become infected with the Toxoplasma parasite each year has raised new concerns about its risks and has prompted a rethink of the dangers posed by cats.

A link between serious mental disorders, including schizophrenia, and the parasite, which is spread by cats, was observed, but studies reported in 2009 and extended in 2011 by a team from the University of Leeds' Faculty of Biological Sciences led by Dr Glenn McConkey provided key genetic evidence that the parasite Toxoplasma gondii could change production of dopamine in the brain.

Disruption of dopamine regulation is believed to be involved in a number of human psychological issues.

The work helped trigger a Food Standards Agency (FSA) review of the threat posed by Toxoplasma that reported this week and attracted wide media interest.

The FSA's Advisory Committee on the Microbiological Safety of Food (ACMSF) recommended further research into routes of Toxoplasma transmission and identification of risks of infection.

Toxoplasmosis is relatively common, with 10-20% of the UK population thought to carry the parasite as cysts. Most people with the parasite do not suffer apparent health problems. However, the impact on high risk groups including unborn children and people with immune deficiencies means that Toxoplasma ranks second among food pathogens in terms of its impact on public health.


Grants

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Dave Lewis, Nigel Hooper, Tony Turner, Hugh Pearson, James Duce, Alzheimer's Society (1/02/2014), £29,871

Sheena Radford, BBSRC (1/10/2013), £329,906

Vas Ponnambalam, Leverhulme Trust (1/09/2013), £245,031

Peter Meyer, EEC (1/09/2013), £242,166

Darren Tomlinson, Leverhulme Trust (1/09/2013), £5,645

Sheena Radford, EEC (1/05/2013), £2,032,465

Michelle Peckham, Gareth Howell, Roman Tuma, David Beech, Nigel Hooper, MRC (1/05/2013), £893,675

Sarah Calaghan, Derek Steele, BHF (1/05/2013), £208,005

Neil Messenger, EPSRC (1/04/2013), £618,675

Lars Jeuken, BBSRC (1/04/2013), £300,633

Ronaldo Ichiyama, MRC (1/04/2013), £270,128

Ian Wood, Dunhill Medical Trust (1/04/2013), £113,705

Paul Millner, Wellcome Trust (1/04/2013), £40,000

Andrew Macdonald, Yorkshire Kidney Research Fund (1/04/2013), £39,886

Samit Chakrabarty, Royal Society (1/04/2013), £15,000

Sarah Zylinski, Royal Society (1/04/2013), £11,000

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