Faculty of Biological Sciences

Publications

Key papers published with the NMR facility in the last 5 years. Please click on the images for links to the relevant publications.

Structure-guided design affirms inhibitors of hepatitis C virus p7 as a viable class of antivirals targeting virion release

Structure-guided design affirms inhibitors of hepatitis C virus p7 as a viable class of antivirals targeting virion release

Conformational properties of the unfolded state of Im7 in nondenaturing conditions.

Conformational properties of the unfolded state of Im7 in nondenaturing conditions.

Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid.

Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid.

Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid.

Ligand binding to distinct states diverts aggregation of an amyloid-forming protein

Ligand binding to distinct states diverts aggregation of an amyloid-forming protein Ligand binding to distinct states diverts aggregation of an amyloid-forming protein

Conformational conversion during amyloid formation at atomic resolution

Conformational conversion during amyloid formation at atomic resolution.

Comparison of Entropic Contributions to Binding in a “Hydrophilic” versus “Hydrophobic” Ligand−Protein Interaction

Comparison of Entropic Contributions to Binding in a “Hydrophilic” versus “Hydrophobic” Ligand−Protein Interaction

Comparison of Entropic Contributions to Binding in a “Hydrophilic” versus “Hydrophobic” Ligand−Protein Interaction

Comparison of Entropic Contributions to Binding in a “Hydrophilic” versus “Hydrophobic” Ligand−Protein Interaction

 

Poxvirus K7 Protein Adopts a Bcl-2 Fold: Biochemical Mapping of Its Interactions with Human DEAD Box RNA Helicase DDX3

Poxvirus K7 Protein Adopts a Bcl-2 Fold: Biochemical Mapping of Its Interactions with Human DEAD Box RNA Helicase DDX3

Poxvirus K7 Protein Adopts a Bcl-2 Fold: Biochemical Mapping of Its Interactions with Human DEAD Box RNA Helicase DDX3

Probing Dynamics within Amyloid Fibrils Using a Novel Capping Method

Probing Dynamics within Amyloid Fibrils Using a Novel Capping MethodProbing Dynamics within Amyloid Fibrils Using a Novel Capping Method

 

Residual Ligand Entropy in the Binding of p-Substituted Benzenesulfonamide Ligands to Bovine Carbonic Anhydrase II

Residual ligand entropy in the binding of p-substituted benzenesulfonamide ligands to bovine carbonic anhydrase II. Residual ligand entropy in the binding of p-substituted benzenesulfonamide ligands to bovine carbonic anhydrase II.

Residual ligand entropy in the binding of p-substituted benzenesulfonamide ligands to bovine carbonic anhydrase II. Residual ligand entropy in the binding of p-substituted benzenesulfonamide ligands to bovine carbonic anhydrase II.